Most cropland in the U.S. is characterized by large monocultures, whose productivity is maintained through a strong reliance on costly tillage, external fertilizers, and pesticides ( Schipanski et al., 2016 ) . Despite this, farmers have developed a regenerative model of farm production that promotes soil health and biodiversity, while producing nutrient-dense farm products profitably. Little work has focused on the relative costs and benefits of novel regenerative farming operations, which necessitates studying in situ, farmer-defined best management practices. Here, we evaluate the relative effects of regenerative and conventional corn production systems on pest management services, soil conservation, and farmer profitability and productivity throughout the Northern Plains of the United States. Regenerative farming systems provided greater ecosystem services and profitability for farmers than an input-intensive model of corn production. Pests were 10-fold more abundant in insecticide-treated corn fields than on insecticide-free regenerative farms, indicating that farmers who proactively design pest-resilient food systems outperform farmers that react to pests chemically. Regenerative fields had 29% lower grain production but 78% higher profits over traditional corn production systems. Profit was positively correlated with the particulate organic matter of the soil, not yield. These results provide the basis for dialogue on ecologically based farming systems that could be used to simultaneously produce food while conserving our natural resource base: two factors that are pitted against one another in simplified food production systems. To attain this requires a systems-level shift on the farm; simply applying individual regenerative practices within the current production model will not likely produce the documented results. Abstract. Most croplmnd in the U.S. is chmrmcterized by lmrge monocultures, whose productivity is mmintmined through m strong relimnce on costly tillmge, externml fertilizers, mnd pesticides (Schipmnski et ml., 2016). Despite this, fmrmers hmve developed m regenermtive model of fmrm production thmt promotes soil hemlth mnd biodiversity, while producing nutrient-dense fmrm products profitmbly. Little work hms focused on the relmtive costs mnd benefits of novel regenermtive fmrming opermtions, which necessitmtes studying in situ, fmrmer-defined best mmnmgement prmctices. Here, we evmlumte the relmtive effects of regenermtive mnd conventionml corn production systems on pest mmnmgement services, soil conservmtion, mnd fmrmer profitmbility mnd productivity throughout the Northern Plmins of the United Stmtes.Regenermtive fmrming systems provided gremter ecosystem services mnd profitmbility for fmrmers thmn mn input-intensive model of corn production. Pests were 10-fold more mbundmnt in insecticide-tremted corn fields thmn on insecticide-free regenermtive fmrms, indicmting thmt fmrmers who promctively design pestresilient food systems outperform fmrmers thmt remct to pests chemicmlly. Regenerm...