Rebuttal From Drs D’Andrilli and Rendina

Commentary: Second ipsilateral metachronous lung cancer: What to do?

“…Although the incidence of a second primary lung cancer occurring ipsilaterally after curative resection is limited to 1% to 2% of patients, this topic carries increasing clinical implications, mainly due to the expanding indications for segmentectomy to treat stage IA NSCLC and to the progressively more frequent early detection of second NSCLC because of improved diagnostic technology and oncologic surveillance. [2][3][4] In this clinical scenario, the present article provides several meaningful scientific messages. The first is that, when feasible, a nonanatomic re-resection can be an adequate therapeutic choice because overall survival and recurrence-free survival results are comparable to those after anatomic reresection, but postoperative morbidity is lower.…”