Rebuttal letter in response to Professor R.H. Anderson's letter ‘Evolution of the vertebrate heart’

Stephenson, Andrea; Adams, Justin W.; Vaccarezza, Mauro

doi:10.1111/joa.12788

Cited by 1 publication

(4 citation statements)

References 15 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…In this regard, Stephenson et al. () had argued that the concept of the helical band was, indeed, ‘validated’ by Buckberg et al. (,b) and Buckberg ().…”

Section: Discussionmentioning

confidence: 98%

“…When discussing the evidence to support the notion that the helical ventricular myocardial band provided a suitable model with which to interpret ventricular function, Stephenson et al. () pointed to the findings revealed by computational modelling of electromechanical propagation within the ventricular cone (Marce‐Nogue et al. ).…”

Section: Findings From Diffusion Tensor Magnetic Resonance Imagingmentioning

confidence: 99%

“…In their response to this letter, they suggested that the concept of the helical band had, indeed, been validated by Buckberg and his colleagues (Stephenson et al. ). They further opined that the model ‘does not have to be correct to be useful’.…”

Section: Introductionmentioning

confidence: 99%

“…Such concerns regarding its anatomical foundation were disregarded by Stephenson et al. () when they responded to a letter recently published in the Journal pointing to its morphological deficiencies (Anderson, ). In their response to this letter, they suggested that the concept of the helical band had, indeed, been validated by Buckberg and his colleagues (Stephenson et al.…”

Section: Introductionmentioning

confidence: 99%

See 3 more Smart Citations

How are the cardiomyocytes aggregated together within the walls of the left ventricular cone?

et al. 2019

View full text Add to dashboard Cite

The manner of packing together of the cardiomyocytes within the walls of the cardiac ventricles has now been investigated for over half a millennium. In 1669, Lower dissected the ventricular mass, likening the arrangement to skeletal musculature, in the form of a myocardial band extending between the right and left atrioventricular junctions. Pettigrew subsequently showed obvious helical arrangements to be evident within the ventricular walls, but emphasised that the cardiomyocytes were attached to each other, and could not justifiably be compared with skeletal cardiomyocytes. Torrent-Guasp then reactivated the notion that the ventricular mass was formed of a solitary band. Unlike Lower, he dissected the band as extending between the pulmonary to the aortic roots. Multiple investigations conducted using gross dissection and histology, and more recently diffusion tensor magnetic resonance imaging and computed tomographic analysis, have shown an absence of any anatomical boundaries within the walls that might permit the mass uniformly to be dissected so as to reveal the band. A response to a recent letter to the Journal, nonetheless, claimed that the dissections had been validated by clinicians interpreting the findings so as to provide an explanation for ventricular cardiodynamics, arguing that the findings provided a suitable anatomical model for this purpose. Anatomical models, however, are of no value unless they are anatomically correct. In this review, therefore, we summarise the evidence showing that the cardiomyocytes making up the ventricular walls, rather than forming a ventricular myocardial band, are instead aggregated together to form a three-dimensional myocardial mesh.

show abstract

“…In this regard, Stephenson et al. () had argued that the concept of the helical band was, indeed, ‘validated’ by Buckberg et al. (,b) and Buckberg ().…”

Section: Discussionmentioning

confidence: 98%

Section: Findings From Diffusion Tensor Magnetic Resonance Imagingmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

See 2 more Smart Citations