Recanalization Rates after Acute Deep Vein Thrombosis: A Single-center Experience Using a Newly Proposed Vein Diameter Variation Index

Brandão, Gustavo Muçouçah Sampaio; Sobreira, Marcone Lima; Malgor, Rafael D.; Rollo, Hamilton Almeida

doi:10.1016/j.avsg.2014.05.013

Cited by 8 publications

(13 citation statements)

References 15 publications

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“…The absence of venous blood flow is a predominant finding in acute stage of DVT but not in chronic. This finding is explained by the high rate of recanalization in chronic DVT as reported by Brandão et al [18].…”

Section: Discussionmentioning

confidence: 70%

Deep Venous Thrombosis: Commonly Affected Veins in the Lower Limbs

Alshoabi¹,

Mothanna²

2019

JBM

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Aim and Objectives: This study aimed to record the commonly affected veins in the lower limbs, to compare the affected sides and gender and to correlate the Doppler findings and stages of deep venous thrombosis (DVT). Materials and Methods: A descriptive retrospective study of 46 already diagnosed cases of lower limb DVT. Results: Out of 46 cases of DVT, 71.74% were females. The majority of patients (93.47%) were affected in unilateral lower limb with significant predominance (65.22%) to affect the left lower limb (p < 0.001). The common femoral vein (CFV) was affected in 71.7% of cases. The superficial femoral vein (SFV) was affected in 71.7% of cases. The popliteal vein was affected in 67.4%. The deep femoral vein was affected only in 17.4%. Both CFV and SFV were affected together in 47.8% of cases. Both SFV and popliteal vein were affected together in 50% of cases. The majority of DVT cases (71.1%) were in the acute stage. This study revealed an essential relationship between the acute stage of DVT and distension of the affected veins (p < 0.001) (OR 20.667, 95% CI 3.826 -111.633). It also detected a significant relationship between the acute stage and absence of venous blood flow (p < 0.001) (OR 90.667,. Conclusion: Lower limb deep venous thrombosis affects left lower limb more than right and females more than males. Superficial femoral vein (SFV) and common femoral vein (CFV) are the most common affected veins. Lower limb DVT predominantly present in acute stage with venous distension and absent blood flow.

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Section: Discussionmentioning

confidence: 70%

Deep Venous Thrombosis: Commonly Affected Veins in the Lower Limbs

Alshoabi¹,

Mothanna²

2019

JBM

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“…It is included in the nosological entity venous thromboembolism (VTE), which encompasses both DVT and pulmonary embolism (PE). 1 Venous thromboembolism occurs in two out of every 1,000 individuals each year, with a rate of recurrence of 25%, 2 while incidence increases to as much as 7 per 1,000 among people over the age of 70 years. 3 It is considered an important cause of morbidity and mortality and requires early diagnosis, because of the risk of progression to PE, 4 which has a mortality rate in the range of 5 to 15%, 2 and to other morbidities such as chronic venous insufficiency and chronic pulmonary hypertension.…”

Section: Introductionmentioning

confidence: 99%

“…After an episode of DVT, an acute inflammatory response occurs in the vein wall and in the thrombus, leading to a dynamic process of thrombus regression by recanalization. 1 This process involves fibrocellular organization of the thrombus, which includes contraction of the thrombus, formation of multiple cracks between thrombus and tunica intima, local fibrinolysis, and fragmentation of the thrombus after cellular invasion by neoformed vessels. 6 Presence of thrombi and the recanalization process can damage venous valves, giving rise to valve incompetence.…”

Section: Introductionmentioning

confidence: 99%

“…Low molecular weight heparins (LMWH) emerged during the 1980s. 1 Up until 2011, the majority of patients were treated using regimens that followed VTE prophylaxis and treatment guidelines that predate the ninth edition of the American College of Chest Physicians' (ACCP) Evidence-Based Clinical Practice Guidelines. In general, treatment of DVT is maintained for around 6 months, depending on patient progress and the thrombus site.…”

Section: Introductionmentioning

confidence: 99%

“…Rivaroxaban and apixaban are employed without initial parenteral anticoagulation, in contrast with dabigatran and the more recent edoxaban, which need initial parenteral anticoagulation. 1,11 Introduction of DOACs into routine clinical practice was supported by the results of many controlled clinical trials, meta-analyses, and real-life studies with large numbers of patients. 11 Several different studies have shown that treatment with DOACs is not inferior to treatment with warfarin in terms of efficacy and safety.…”

Section: Introductionmentioning

confidence: 99%

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Análise do grau de recanalização da trombose venosa profunda: estudo comparativo de pacientes tratados com varfarina versus rivaroxabana

et al. 2019

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Resumo Contexto A trombose venosa profunda (TVP) afeta anualmente cerca de dez milhões de pessoas no mundo e tem como principais complicações a embolia pulmonar e a síndrome pós-trombótica. O tratamento padrão é a anticoagulação, que pode ser realizada com heparinas, antagonistas da vitamina K, fondaparinux ou, mais recentemente, com anticoagulantes orais diretos (direct oral anticoagulants, DOACs). Os anticoagulantes diminuem a progressão do trombo e facilitam os mecanismos trombolíticos naturais, fato conhecido como recanalização, que pode ocorrer em graus e tempos variados, influenciados por diversos fatores, dentre eles o tipo de anticoagulação utilizado. Objetivos Avaliar o grau e o tempo de recanalização através da análise de laudos de eco-Doppler colorido (EDC) de pacientes com TVP tratados com DOACs ou com heparina + varfarina. Métodos Foram avaliados retrospectivamente os dados demográficos e os laudos dos EDC dos pacientes com TVP, tratados entre janeiro de 2009 a dezembro de 2016. Os pacientes foram divididos em dois grupos, de acordo com a terapêutica utilizada: Grupo I (heparina + varfarina): 26 pacientes; Grupo II (rivaroxabana): 51 pacientes. Os principais itens observados foram o grau e o tempo para a recanalização. Resultados Foram observadas taxas de recanalização aos 30, 90 e 180 dias de 10%, 52,5% e 78,9%, respectivamente, no Grupo I, e de 55,3%, 83,5% e 92,4%, respectivamente, no Grupo II, com diferença estatisticamente significativa (p = 0,041). Conclusões Ambos os tratamentos promoveram recanalização. Houve recanalização mais precoce no grupo de pacientes que utilizaram a rivaroxabana.

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Removal of contaminant in electroplating wastewater and its toxic effect using biosynthesized silver nanoparticles

2022

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This research is designed to remove contaminant in electroplating wastewater, using biosynthesize silver nanoparticles (SNPs) and to determine its in-vivo toxic effect. Silver nanoparticles (SNPs: 1,2,3 and 4) synthesized at different conditions and characterised, yielded spherical shapes of irregular sizes comprising of − OH, − C=C, − C=O, − C–H and − NO functional groups. The electroplating wastewater treated with the synthesized SNPs, were subjected to physicochemical analysis which revealed the ability of the SNPs to remove pollutants, with SNP4 displaying a higher affinity. The haematological investigation disclosed no significant impact on haemoglobin, packed cell volume, mean corpuscular haemoglobin concentration, red blood cell, neutrophils and lymphocytes compared to the control group. Although, the liver tissues revealed toxic effects of the treated wastewater. The study validates that the biosynthesized SNPs contained stabilizing and reducing agent and also has the ability to eliminate pollutant in electroplating wastewater. Article highlights Spherical shaped SNPs exhibits loosely bound properties and aggregation. SNPs contained functional groups acting as stabilizing and reducing agent. The SNPs treated wastewater had no significant impact on haemoglobin, packed cell volume and red blood cell in rats. The synthesized SNPs had the ability to remove contaminant from the electroplating wastewater.

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Recanalization Rates after Acute Deep Vein Thrombosis: A Single-center Experience Using a Newly Proposed Vein Diameter Variation Index

Cited by 8 publications

References 15 publications

Deep Venous Thrombosis: Commonly Affected Veins in the Lower Limbs

Deep Venous Thrombosis: Commonly Affected Veins in the Lower Limbs

Análise do grau de recanalização da trombose venosa profunda: estudo comparativo de pacientes tratados com varfarina versus rivaroxabana

Removal of contaminant in electroplating wastewater and its toxic effect using biosynthesized silver nanoparticles

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