Recent achievements in intermolecular sp3 C–H bond functionalization of organic compounds by superelectrophilic trihalomethyl metal complex

A comparative study of inter- and intramolecular C–H aminations: mechanism and site selectivity

“…[11][12][13][14] Atom-, time-, and cost-efficient opportunities have made the eld of C-H amination an active area of research. [15][16][17][18][19][20] In general, C-H amination is principally divided into two types: 7 intra- [21][22][23] and intermolecular [24][25][26] aminations. Relative to the large number of catalysts available for intramolecular amination, only a few transition-metal complexes can be employed effectively to catalyze the corresponding intermolecular reaction.…”

Insight into the mechanism and site-selectivity of Rh2II,II(esp)2-catalyzed intermolecular C–H amination

“…[8][9][10][11][12][13] Therefore, the controllable intermolecular amiantion reaction is a more attractive and powerful chemical process for introducing a nitrogen group into the non-activated C-H bond of alkanes. [14][15][16][17][18] Now, although a high site-, enantioand chemoselectivity can be assured by the intramolecular nitrenoid delivery, [19][20][21][22][23] devising a similar discrimination process at the intermolecular C-H insertion site is much more challenging [24][25][26][27] due to the increased degree of freedom, which will lead to a more complex amination mechanism. [28][29][30][31][32] Moreover, the relative experiments reported by J.…”