Recent advancements of fluorescent biosensors using semisynthetic probes

Reja, Shahi Imam; Minoshima, Masafumi; Hori, Yuichiro; Kikuchi, Kazuya

doi:10.1016/j.bios.2023.115862

Biosensors and Bioelectronics

2024

DOI: 10.1016/j.bios.2023.115862

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Recent advancements of fluorescent biosensors using semisynthetic probes

Shahi Imam Reja,

Masafumi Minoshima,

Yuichiro Hori

et al.

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2024

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Cited by 6 publications

References 143 publications

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Microneedle sensors for dermal interstitial fluid analysis

Kim,

Ahn,

Chaj Ulloa

et al. 2024

Med-X

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The rapid advancement in personalized healthcare has driven the development of wearable biomedical devices for real-time biomarker monitoring and diagnosis. Traditional invasive blood-based diagnostics are painful and limited to sporadic health snapshots. To address these limitations, microneedle-based sensing platforms have emerged, utilizing interstitial fluid (ISF) as an alternative biofluid for continuous health monitoring in a minimally invasive and painless manner. This review aims to provide a comprehensive overview of microneedle sensor technology, covering microneedle design, fabrication methods, and sensing strategy. Additionally, it explores the integration of monitoring electronics for continuous on-body monitoring. Representative applications of microneedle sensing platforms for both monitoring and therapeutic purposes are introduced, highlighting their potential to revolutionize personalized healthcare. Finally, the review discusses the remaining challenges and future prospects of microneedle technology. Graphical Abstract

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Microneedle sensors for dermal interstitial fluid analysis

Kim,

Ahn,

Chaj Ulloa

et al. 2024

Med-X

View full text Add to dashboard Cite

show abstract

Constructing a label-free electrochemical biosensor based on magnetic α-Fe2O3/Fe3O4 heterogeneous nanosheets for the sensitive detection of VKORC1*2 gene

Wang,

Ouyang,

et al. 2024

Arabian Journal of Chemistry

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Recent Progress in DNA Biosensors for Detecting Biomarkers in Living Cells

Dong,

Su,

et al. 2024

ACS Biomater. Sci. Eng.

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Analysis of biomarkers in living cells is crucial for deciphering the dynamics of cells as well as for precise diagnosis of diseases. DNA biosensors employ DNA sequences as probes to offer insights into living cells, and drive progress in disease diagnosis and drug development. In this review, we present recent advances in DNA biosensors for detecting biomarkers in living cells. The basic structural components of DNA biosensors and the signal output method are presented. The strategies of DNA biosensors crossing the cell membrane are also described, including coincubation, nanocarriers, and nanoelectroporation techniques. Based on biomarker categorization, we detail recent applications of DNA biosensors for detecting small molecules, RNAs, proteins, and integrated targets in living cells. Furthermore, the future development directions of DNA biosensors are summarized to encourage further research in this growing field.

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Recent advancements of fluorescent biosensors using semisynthetic probes

Cited by 6 publications

References 143 publications

Microneedle sensors for dermal interstitial fluid analysis

Microneedle sensors for dermal interstitial fluid analysis

Constructing a label-free electrochemical biosensor based on magnetic α-Fe2O3/Fe3O4 heterogeneous nanosheets for the sensitive detection of VKORC1*2 gene

Recent Progress in DNA Biosensors for Detecting Biomarkers in Living Cells

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