Recent advances and applications of the lipolytic activity of Carica papaya latex

Plant latex lipase as biocatalysts for biodiesel production

“…papaya lipase (CPL) represents an emerging and versatile biocatalyst (Domínguez de María et al, 2006). This fact is confirmed from the high number of applications described in recent years (Foglia and Villeneuve, 1997a;Mangos et al, 1999;Campillo-Alvarado and Tovar-Miranda, 2013). Its availability as a "natural immobilized" catalyst, combined with a competitive price, makes CPL a promising catalyst in the biotransformations field.…”

“…Consequently, if incisions are made in those aerial parts, especially in the unripe fruits, an abrupt release of latex (the so-called C. papaya latex) is observed. This latex is a thixotropic fluid with a milky appearance, which contains around 15% of dry matter, 85% water, and a great variety of hydrolytic enzymes, mainly proteases (El Moussaoui et al, 2001;Azarkan et al, 2003;Campillo-Alvarado and Tovar-Miranda, 2013). Furthermore, different protein compositions have been reported depending on the age or sex of the tree, as well as on the time of day in which the tapping is carried out (Luis Madrigal et al, 1980;Caro et al, 2000).…”

Screening of Novel Materials for Biodiesel Production Through the Esterification of Oleic Acid

“…In this sense, some plant latex-producing families such as Caricaceae, Euphorbiaceae, and Apocynaceae showed lipase activity [10]. From these lipases, Carica papaya latex lipase (CPL) has been, by far, the most studied in different industrial applications due to the abundance of this resource, its easy production and versatility [11]. Araujia sericifera (Apocynaceae), a native Argentinean milkweed which contains at least three proteases as some of their water-soluble components of its latex, showed also lipase activity in the insoluble fraction [12,13].…”

Lipase‐Catalyzed Kinetic Resolution of (±)‐1‐(2‐Furyl) Ethanol in Nonaqueous Media

“…Especially, lipase‐catalyzed kinetic resolution has been well adapted for preparation of single isomeric compounds such as secondary alcohol, acid, and amine through esterification/transesterification and hydrolytic reactions, respectively. Lipases offer high chemo‐, regio‐, and stereoselectivity, accept a repertoire of compounds, function without expensive cofactors, and are commercially prepared from different species like microbes, animals, and plants . Further, the use of organic and neoteric solvent as reaction media for the lipase‐catalyzed reaction widens the scope, including greater solubility of organic molecules, enhanced stability of enzymes, and ease of recovery of product and catalyst as compared to aqueous media …”

“…Lipases offer high chemo-, regio-, and stereoselectivity, accept a repertoire of compounds, function without expensive cofactors, and are commercially prepared from different species like microbes, animals, and plants. [9][10][11] Further, the use of organic and neoteric solvent as reaction media for the lipase-catalyzed reaction widens the scope, including greater solubility of organic molecules, enhanced stability of enzymes, and ease of recovery of product and catalyst as compared to aqueous media. 12,13 The optically active S-enantiomer of 1-(2-furyl) ethanol is used as an important building block for the synthesis of various natural products such as flavonoids, polyketide antibiotics, and carbohydrate derivatives.…”