“…Therefore, the large values of the polarizability of our stable therapeutic nanostructures show that they have excellent binding affinity. As regards the hyperpolarizability, nonlinear optical properties have applications in the second [ 71 , 72 ] and third harmonics generation [ 63 ] (SHG and THG), in drug delivery imaging [ [72] , [73] , [74] ], in the pharmaceutical and biopharmaceutical field [ 61 , 62 , 64 ]. NLO imaging is thus a technology with great potential for pharmaceutical analysis.…”