Recent advances and potential applications for metal-organic framework (MOFs) and MOFs-derived materials: Characterizations and antimicrobial activities

Hubab, Muhammad; Al-Ghouti, Mohammad A.

doi:10.1016/j.btre.2024.e00837

Biotechnology Reports

2024

DOI: 10.1016/j.btre.2024.e00837

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Recent advances and potential applications for metal-organic framework (MOFs) and MOFs-derived materials: Characterizations and antimicrobial activities

Muhammad Hubab,

Mohammad A. Al-Ghouti

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2024

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Cited by 6 publications

References 228 publications

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ZIF‐8 as Potential Vector for Enhanced Target Delivery of Sulfathiazole for the Treatment of Bovine Ruminal Acidosis

di Nicola,

Paolucci,

Daniele

et al. 2024

Eur J Inorg Chem

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The aim of this paper is enlarging the potential use of ZIF‐8 MOF as drug delivery system (DDS) for antimicrobial molecules, in particular for sulfathiazole, to be employed for the treatment of Subacute Ruminal Acidosis (SARA) in dairy cows. We therefore optimized (from milligrams to grams) the synthesis methodology for ZIF‐8 MOF, moving from organic solvents to aqueous solution, deeply characterizing the prepared material with X‐ray diffraction (XRD), surface area analyses (BET), electron microscopy (SEM), and thermogravimetric analyses (TGA). Once proved that the synthesis is also reproducible, we tested the stability of the material at physiological and acid pH, controlling material stability over time by checking their crystallinity with XRD. We then optimized sulfathiazole entrapment method to obtain the best material, checking the effective loading with UV‐vis spectroscopy. Afterwards, we checked the effective entrapment vs physical mixture by means of XRD, SEM and ATR‐MIR spectroscopy. Finally we tested the pH‐responsive drug release by dialyzing the sulfathiazole@ZIF‐8 by UV spectroscopy on the dialysis solution, confirming the strong pH‐dependence of release time of sulfathiazole.

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ZIF‐8 as Potential Vector for Enhanced Target Delivery of Sulfathiazole for the Treatment of Bovine Ruminal Acidosis

di Nicola,

Paolucci,

Daniele

et al. 2024

Eur J Inorg Chem

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show abstract

Exploring metal-organic frameworks (MOFs) in drug delivery: A concise overview of synthesis approaches, versatile applications, and current challenges

Vikal,

Maurya,

Patel

et al. 2024

Applied Materials Today

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Advances in immobilized microbial technology and its application to wastewater treatment: A review

Hou,

Hu,

Huang

et al. 2024

Bioresource Technology

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Recent advances and potential applications for metal-organic framework (MOFs) and MOFs-derived materials: Characterizations and antimicrobial activities

Cited by 6 publications

References 228 publications

ZIF‐8 as Potential Vector for Enhanced Target Delivery of Sulfathiazole for the Treatment of Bovine Ruminal Acidosis

ZIF‐8 as Potential Vector for Enhanced Target Delivery of Sulfathiazole for the Treatment of Bovine Ruminal Acidosis

Exploring metal-organic frameworks (MOFs) in drug delivery: A concise overview of synthesis approaches, versatile applications, and current challenges

Advances in immobilized microbial technology and its application to wastewater treatment: A review

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