Recent advances in 1,4-benzoquinone chemistry

Abstract

As 1,4-benzoquinonas são encontradas em toda a natureza, podendo ser sintetizadas por diversas estratégias. Esta revisão apresenta os desenvolvimentos recentes das metodologias de síntese, das reações de ciclo adição, da química computacional e dos estudos de pulso radiolítico. Destaca ainda a sua significância química e biológica e de seus compostos derivados.1,4-Benzoquinones are ubiquitous in nature and can be synthesized by diverse strategies. Recent developments on their synthetic methodologies, cycloaddition reactions, computational chemistry and pulse radiolytic studies are reported in this review. Their chemical and biological significance as well as their derivates' are also covered.

Harvestman Phenols and Benzoquinones: Characterisation and Biosynthetic Pathway

“…In addition to harvestmen, naturally occurring 1,4-benzoquinones with great structural variety are also found in bacteria, plants and other arthropod orders [15,16]. They are known to be toxic and therefore are employed by beetles [17][18][19][20], earwigs [21], termites [22] and harvestmen [12,13] as a defence against natural predators.…”

Fungal biosynthesis of the bibenzoquinone oosporein to evade insect immunity

“…Beauveria bassiana | bibenzoquinone | oosporein | biosynthesis | virulence Q uinones are ubiquitous in living organisms such as bacteria, fungi, plants, and humans, and a large number of derivatives containing either a 1,2-benzoquinone or 1,4-benzoquinone backbone have been shown to express an array of bioactive or pharmaceutical-relevant activities (1,2). However, only a handful quinone biosynthetic pathways have been characterized.…”

Laccase-catalyzed synthesis of 2,3-ethylenedithio-1,4-quinones

“…1). Compounds containing quinones are present all throughout nature and in many biologically active natural products [7]. The compounds synthesized in this study are no different.…”