Recent advances in catalytic C−H borylation reactions

Pd-catalyzed coupling reactions of anhydro-aldose tosylhydrazones with aryl bromides to produce substituted exo -glycals

“…In most of the above methods base stable protecting groups had to be applied and/or the reagents like boronic acids [23] or stannanes [24] needed be prepared from aryl halides. In the present work we have investigated the formation aryl substituted exo-glycals E in the first Pdcatalyzed cross coupling reactions of ester or ether protected anhydro-aldose tosylhydrazones H with easily available aryl bromides.…”

A Cyclam‐Based Fluorescent Ligand as a Molecular Beacon for Cu2+ and H2S Detection

“…[71] The behavior of py-cyclam-pyr-Cu in the presence of NaSH is thus very similar to that reported for several related Cu 2+ complexes. [22][23][24][25][26][29][30][31]33,70]…”

“…Their working principle exploits copper-mediated precipitation of sulfide, with subsequent release of the organic ligand, which restores the initial fluorescence intensity of the free ligand. [22,23,25,26,[29][30][31][32][33] H 2 S is a molecule, which has recently gained renewed interest, owing to the discovery that it covers a variety of biological functions. [34][35][36] Furthermore, intracellular H 2 S le-vels, generated in response to physiological stimuli, are still controversial.…”

Iridium(I)‐Catalyzed C−H Borylation in Air by Using Mechanochemistry

“…C−H borylation reactions have become an especially important synthetic method because they provide straightforward access to a great variety of functionalized organoboron compounds . In particular, iridium(I)‐catalyzed aromatic C−H borylation reactions have proven to be one of the most efficient methods, which is widely used in the synthesis of complex molecules (Scheme a) . However, despite the significant progress, the exploration of new concepts and reaction media to improve the sustainability of such C−H borylation transformations remains crucial .…”

“…In particular, iridium(I)‐catalyzed aromatic C−H borylation reactions have proven to be one of the most efficient methods, which is widely used in the synthesis of complex molecules (Scheme a) . However, despite the significant progress, the exploration of new concepts and reaction media to improve the sustainability of such C−H borylation transformations remains crucial . In this context, the use of significant amounts of dry and degassed organic solvents and the need to operate under an atmosphere of inert gas are still important limiting factors.…”