Recent advances in cholesterol biosensor

Cholesterol Self-Powered Biosensor

“…CardioCheck "Cholesterol and glucose test monitors" by Polymer Techology Systems Inc. (PS-003528 ER1 1005), Cholestrack "Cholesterol Testers" by AccuTech, LLC, USA (US Pat. № 5340539) 4 .…”

“…Different design strategies have been utilised for the development of electrochemical cholesterol biosensors including oxidation by mediated ChOx [5][6][7][8][9][10] or hydrogen peroxide monitoring by horse radish peroxidase 11,12 or by inorganic catalysts 13 and nanostructures [14][15][16] . Despite of the variety of reported cholesterol electrochemical biosensors 4 , only few of them have been shown to operate in whole blood [17][18][19] . An amperometric biosensor based on ChOx entrapped inside a composite polypyrrole-hydrogel membrane showed excellent correlation with results obtained by the standard method 17 for total cholesterol determination in cholesterol esterase (ChEt) pretreated serum samples.…”

Cholesterol Oxidase: Source,Properties and Applications.

“…In addition to being used in the microanalysis of steroids in food samples it is also used for differentiating the steric configurations of 3-ketosteroids from the corresponding 3 β-hydroxysteroids [101]. In recent years, various electrochemical biosensors are being designed by using immobilized CHOx for the determination of cholesterol in serum or food samples [82,88,102].…”

“…Biosensors with immobilized enzymes are getting huge interest in analytical technology as they facilitate the enzyme reuse as well as demonstrate the exclusive selectivity of the biological molecules and the processing power of modern microelectronics [81]. In the recent years, a variety of cholesterol biosensors have been developed [88]. Most of the reported cholesterol biosensors are based on amperometric technique besides, cholesterol biosensors based on photometric behaviors like luminescence, fluorescence and surface plasmon resonance (SPR) have also been reported [88,114,115].…”

“…In the recent years, a variety of cholesterol biosensors have been developed [88]. Most of the reported cholesterol biosensors are based on amperometric technique besides, cholesterol biosensors based on photometric behaviors like luminescence, fluorescence and surface plasmon resonance (SPR) have also been reported [88,114,115]. Amperometric measurement of O 2 consumption or H 2 O 2 production during cholesterol catalysis by CHOx is the frequently used strategy in cholesterol assay in the samples [116].…”