Recent Advances in Cobalt‐catalyzed Functionalization of Unactivated Olefins

Abstract

Olefins are low-cost starting materials that may be obtained in bulk quantities from petrochemical feedstocks and renewable resources. The transition metal-catalyzed unactivated olefin functionalization is well explored and received an extensive interest from synthetic chemists. In recent times, chemists have successfully employed different transition metals for the functionalization of unactivated olefins. Among the different transition metals that have been used, cobalt catalysts have received great attention from synthetic chemists for CÀ H functionalization reactions, owing to their ready availability and high reactivity. Herein, we discuss the most recent reports in the field of cobaltcatalyzed functionalization of unactivated olefins that enable CÀ C, CÀ X and CÀ hetero bond formation and covers the literature from 2016 to 2021.

The recent advances in cobalt-catalyzed C(sp3)–H functionalization reactions

“…Hence, there is an apparent need to explore and develop alternative catalysts that provide acceptable yields under feasible reaction conditions. The 1 st -row transition metal-based catalysts like manganese, 4 iron, 5 cobalt, 6 nickel, 7 and copper 8 are attracting the attention of several organic chemists due to their appealing properties like high abundance, low cost, and low toxicity. As every catalytic system is fundamentally different, not every transition metal-based catalyst can furnish the desired results.…”

Cobalt-Catalyzed Divergent Cycloadditions of Alkynes with Conjugated Dienes Yielding 3-Vinylcyclobutenes, Bicyclo[3.1.0]hexenes, and Cyclohexa-1,4-dienes

“…Alkynes and conjugated dienes have attracted considerable attention as useful building blocks in transition-metal complex catalysis . Hilt and co-workers reported a pioneering reaction, a Co-catalyzed cycloaddition of alkynes with conjugated dienes, in which the [CoBr 2 (dppe)]/Zn/ZnI 2 system catalyzed the Diels–Alder type [2 + 4] cycloaddition of nonactivated alkynes with conjugated dienes under ambient conditions (Scheme a) .…”