Recent Advances in Dual Disorders (Addiction and Other Mental Disorders)

Torrens, Marta; Adán, Ana

doi:10.3390/jcm12093315

Cited by 3 publications

(2 citation statements)

References 17 publications

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“…In addition, it is noted that alcohol use disorder is highly comorbid with other psychiatric disorders, such as depression or personality disorder, 88 as was also found within some of the studies included. This, so-called “dual disorder”, 89 , 90 is associated with poorer prognosis (eg, greater psychopathological severity, higher frequency of psychiatric admissions) and may be accompanied by other, distinct, neuropsychological characteristics. 91 …”

Section: Discussionmentioning

confidence: 99%

“…Studies within this review show considerable differences in the number of variables included in their analyses. In this regard, we notice that well-controlled, cross-sectional studies, including multiple relevant variables associated with neurocognitive functioning in abstinent AUD, also contribute to our understanding of neurocognitive recovery (see for example 90 ) but have not been included in this review. Second, we did not pool data to meta-analyze the effects of individual factors since not all data were available from the included studies.…”

Section: Limitationsmentioning

confidence: 99%

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Neurocognitive Recovery in Abstinent Patients with Alcohol Use Disorder: A Scoping Review for Associated Factors

Staudt,

Kok,

de Haan

et al. 2023

NDT

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Objective Studies have reported inconsistent results regarding the extent to which neurocognitive recovery occurs in abstinent patients with alcohol use disorder (AUD). In addition to abstinence, other factors may have influenced this process and contributed to the inconsistencies. This review examines the factors investigated in this regard and describes the possible influence of each factor based on the evidence collected. Methodology PubMed was systematically searched for articles published between January 2000 and July 2023. Longitudinal humane studies investigating neurocognitive recovery in abstinent adult AUD patients were included. Studies with a cross-sectional design were excluded, as were studies that did not classify AUD according to the DSM-IV or 5 criteria, only examined binge use, did not report neuropsychological outcomes or duration of abstinence, or where neurological disorders were present. Results Sixteen categories of factors were distinguished from 31 full-text articles. Consistent patterns were found, indicating an association between neurocognitive recovery and the “smoking” and ‘brain volume” factors. Consistent patterns were also found indicating that there is no relationship with “quantities of alcohol used” and “education level.” A similar consistent pattern was also found for “polysubstance use”, “gender” and “verbal reading”, but the number of studies is considered limited. The association with “age” is studied frequently but with inconsistent findings. The remaining eight factors were regarded as understudied. Conclusion The clearest patterns emerging from the evidence are a predominantly negative influence of smoking on neurocognitive recovery, associations between changes in brain area volume and neurocognitive recovery, and no association between neurocognitive recovery and the amount of alcohol consumed, as measured by self-report, nor with educational attainment. Future research on the understudied factors and factors with inconsistent evidence is needed, preferably through longitudinal designs with multiple assessment periods starting after at least two weeks of abstinence.

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