“…GC×GC is currently one of the most effective techniques for the separation and analysis of environmental samples, offering significantly greater peak capacities than conventional chromatographic methods. GC×GC provides three major benefits, namely, enhanced chromatographic separation, improved sensitivity by effect of cryofocusing with the thermal modulator, and chemical class ordering in the contour plot (Ballesteros- Gomez & Rubio, 2011). Research in GC×GC has recently shifted from instrumental development to application to real samples over the last four years especially with the coupling to MS. Nearly 83% of the over 110 research articles published (specify the type or classification of articles) in 2010 were devoted to applications of GC×GC (Edwards et al, 2011).…”