2009
DOI: 10.4236/jbise.2009.25046
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Recent advances in fiber-optic DNA biosensors

Abstract: Fiber-optic DNA biosensors are a kind of analytic setups, which convert the Waston-Crick base pairs matching duplex or Hoogsteen's triplex (T/A-T, C/G-C) formation into a readable analytical signals when functionalized singlestrands DNA (ssDNA) or double-strands DNA (dsDNA) of interest are immobilized on the surface of fiber-optic hybrids with target DNA or interacts with ligands. This review will provide the information about the fiber-optic DNA biosensors classified into two categories depending on the end f… Show more

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Cited by 14 publications
(4 citation statements)
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References 62 publications
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“…The NATOF is fabricated by heat pulling method, utilizing a CO 2 laser [1][2]. For tapering the CO 2 laser beam focused via a Zn-Se lens on the fiber length.…”
Section: Resultsmentioning
confidence: 99%
“…The NATOF is fabricated by heat pulling method, utilizing a CO 2 laser [1][2]. For tapering the CO 2 laser beam focused via a Zn-Se lens on the fiber length.…”
Section: Resultsmentioning
confidence: 99%
“…Optical fibre biosensors have been widely exploited for the detection of a board range of analytical targets, including viruses, spores, bacterial pathogens, pesticides, toxins and other small molecules from clinical and food samples (Bhunia, 2014;Bosch et al, 2007;Liu et al, 2014;Marazuela and Moreno-Bondi, 2002;Urrutia et al, 2015;Velusamy et al, 2010;Wang et al, 2009). The working principle of the optical fibre biosensors and their applications are well known and have been extensively reviewed (Bosch et al, 2007;Chen and Ding, 2013;Marazuela and Moreno-Bondi, 2002;Wang andWolfbeis, 2016, 2013).…”
Section: Optical Fibre Biosensorsmentioning
confidence: 99%
“…Biosensors based on fluorescence resonance energy transfer (FRET) technology, which are used in probe-based assays for quantitative PCR (qPCR), make use of the transfer of energy from a donor fluorophore to an acceptor fluorophore when appreciable overlap exists between the absorption spectrum of the acceptor and the emission spectrum of the donor. This technology has also been used in screening gene mutations, measuring gene expression, and in quantifying viral loads [ 34 , 35 , 36 , 37 ].…”
Section: Dna-based Nanobiosensors For Detection Of Infectious Disementioning
confidence: 99%