Recent Advances in Herbal-Derived Products with Skin Anti-Aging Properties and Cosmetic Applications

Abstract

Although aesthetic benefits are a desirable effect of the treatment of skin aging, it is also important in controlling several skin diseases, mainly in aged people. The development of new dermocosmetics has rapidly increased due to consumers’ demand for non-invasive products with lower adverse effects than those currently available on the market. Natural compounds of plant origin and herbal-derived formulations have been popularized due to their various safe active products, which act through different mechanisms of action on several signaling pathways for skin aging. Based on this, the aim of the review was to identify the recent advances in herbal-derived product research, including herbal formulations and isolated compounds with skin anti-aging properties. The studies evaluated the biological effects of herbal-derived products in in vitro, ex vivo, and in vivo studies, highlighting the effects that were reported in clinical trials with available pharmacodynamics data that support their protective effects to treat, prevent, or control human skin aging. Thus, it was possible to identify that gallic and ferulic acids and herbal formulations containing Thymus vulgaris, Panax ginseng, Triticum aestivum, or Andrographis paniculata are the most promising natural products for the development of new dermocosmetics with skin anti-aging properties.

A study of anti‐wrinkle functions and improvement of cream with Phaseolus angularis

“…Non-enzyme antioxidants include vitamin C, vitamin E, β-Carotene, flavonoids, etc. [18][19][20]. Existing antioxidant components in topical products include selenium, flavonoids, vitamin C, carotenoid, vitamin E and coenzyme Q10 [21].…”

Efficacy and Safety of Phaseolus angularis L for. as Anti- aging Therapy in Healthy Skin

“…Enzyme antioxidants include catalase, superoxide dismutase, glutathione peroxidase, glutathione S-transferase, etc. Nonenzyme antioxidants include vitamin C, vitamin E, β-Carotene, avonoids, etc [17][18][19]. Existing antioxidant components in topical products include selenium, avonoids, vitamin C, carotenoid, vitamin E, and coenzyme Q10 [20].…”

Anti-elastase, anti-tyrosinase and anti-inflammatory activities of three compounds isolated from Psorospernum aurantiacum Engl. : in- silico and in- vitro assays

“…Therefore, the need for the discovery and the development of new strategies to halt skin aging has become a necessity Natural compounds of plant origin have been screened for their skin anti-aging abilities. In this regard, L-ergothioneine and lentinan from mushroom have been known to exert strong antioxidant and anti-in ammatory activities, respectively ; Ferulic acid from several plant origin have been reported to enhance skin elasticity; astragalin-2'',6''-di-O-gallate from Rosa rugosa has been shown signi cant antioxidant, antibacterial, elastase and tyrosinase inhibitory activities; Batatasin III from Dendrobium loddigesii was found to increase collagen synthesis (Costa et al, 2022; Jing Xie et al, 2022; Tao q et al, 2016). Products with safety and e cacy based on natural bioactive compounds in cosmetics remain scarce, other natural anti-skin agents need to be investigated.…”