Recent Advances in K-SPR Sensors for the Detection of Biomolecules and Microorganisms: A Review

Uniyal, Shikha; Choudhary, Kuldeep; Sachdev, Surbhi; Kumar, Santosh

doi:10.1109/jsen.2022.3172115

Cited by 26 publications

(11 citation statements)

References 100 publications

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“…[24,25] The response of the Au/Co/Au sensor toward the magnetic field with 0, 6, 9, and 12 nm Co layers was 0, 4219.29, 76.89, and 43.68 mT unit reflectivity À1 (saturation magnetization strength approximately 40 mT from Figure 7d), better than the previous report. [26][27][28][29][30] The ultrahigh response is attributed to the strong local electric field on the surface of the Au/Co/Au film under the surface plasmon resonance (Figure 5). [31,32] The full width at half maxima (FWHM), a pivotal point to evaluate the sensing characteristic of the SPR sensor, of Au/Co/Au magnetic sensor with different thicknesses of Co layer (0, 6, 9, 12 nm) is 0, 8.8, 11.9, 12.4, and 12.6, respectively, which rises with the thickness of Co increase, due to the ohmic loss of Co.…”

Section: Resultsmentioning

confidence: 99%

Magnetic Field Sensor Based on Magnetic Optical Surface Plasmon Resonance

Liu

Wang

Zhang

2023

Advanced Photonics Research

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Surface plasmon resonance with high sensitivity is widely used in molecular dynamics detection. Herein, a magneto‐optic surface plasmon resonance (MOSPR) sensor based on Au/Co/Au thin film for detecting magnetic fields is developed. The strong coupling between the magneto‐optical waveguide mode and the surface plasmon resonance mode is analyzed and the linear relationship between the reflectivity of the MOSPR sensor and the magnetic field is established. The response, response–recovery time, and dispersion relationship for different magnetic fields are also numerically simulated. Additionally, experimental data on the MOSPR sensor's response to magnetic fields at room temperature (25 °C) are obtained. During the experiment, a differential signal in the light path is applied to reduce the noise generated by the environment. The results demonstrate that the MOSPR sensor exhibits high response, ultrafast response time, and long‐term stability. The study provides a promising approach for detecting magnetic fields with high sensitivity and accuracy.

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Section: Resultsmentioning

confidence: 99%

Magnetic Field Sensor Based on Magnetic Optical Surface Plasmon Resonance

Liu

Wang

Zhang

2023

Advanced Photonics Research

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“…Within field of biosensing, the SMS fiber structure has emerged as a versatile platform for real-time very highly sensitive biomolecules detection [6,7]. This innovative optical fiber configuration consists of a multi-mode fiber of length 2.3 cms [8] sandwiched between two single mode fiber sections of length 20 cms as shown in Fig. 1.…”

Section: Fabrication Of Sms Fiber Sensor Structurementioning

confidence: 99%

Optical fiber-based LSPR biosensor for enhanced dopamine detection: advancing personalized healthcare

Sharma,

Choudhary,

Gupta

et al. 2024

Optical Fibers and Sensors for Medical Diagnostics, Treatment, and Environmental Applications XXIV

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Dopamine, a vital neurotransmitter in the human body, plays a crucial role in various physiological functions and is closely associated with neurological disorders such as Parkinson's disease. Timely and accurate detection of dopamine levels is essential for effective disease management and personalized healthcare. In this study, we propose an innovative optical fiber-based biosensor utilizing the Localized Surface Plasmon Resonance (LSPR) effect for highly sensitive and selective dopamine detection. The biosensor probe is fabricated using a SMS (Single mode fiber-Multimode fiber-Single mode fiber) optical fiber structure, which is chemically modified to enhance the LSPR effect. Gold nanoparticles are employed to amplify the plasmonic response, enabling improved sensing performance. Experimental analysis is performed using dopamine samples, and the results are obtained using a spectrometer. The developed LSPR biosensor demonstrates great potential for precise and efficient dopamine detection, paving the way for advanced personalized healthcare and improved management of neurological disorders.

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“…Although these methods are good in term of selectivity and sensitivity but are complex and inefficient in terms of cost and time. Hence, an uncomplicated and fast method is required to develop point of care approach for detection of vitamin C. The development of highly sensitive, extremely simplistic and quite speedy optical fiber biosensors (OFBs) is one such step towards effective and efficient biosensing of vitamin C. Localized Surface Plasmon Resonance (LSPR) based OFBs (L-OFBs) have been a part of extensive research for biosensing utilities in living beings [11]. In LSPR based OFBs, optical fiber structures are coated with metal nanoparticles and consequently the surface resonance phenomenon remains confined to a limited reduced space.…”

Section: Introductionmentioning

confidence: 99%

Optical sensing of vitamin C concentrations: a novel approach with etched fiber-based plasmon sensor

Choudhary,

Subbanna,

Uniyal

et al. 2024

Nanoscale Imaging, Sensing, and Actuation for Biomedical Applications XXI

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Vitamin C, or ascorbic acid, is a vital nutrient with significant implications for human health. Accurate and rapid detection of vitamin C concentrations in various samples holds immense importance in medical, pharmaceutical, and food industries. In this study, we introduce a novel approach utilizing an etched fiber-based plasmon sensor for sensitive and selective detection of vitamin C. The biosensor employs a gold-coated optical fiber with a precisely etched region, enabling the excitation of surface plasmon polaritons (SPPs). The interaction between SPPs and the vitamin C analyte induces changes in the refractive index near the fiber surface, consequently causing shifts in the resonance wavelength of the plasmonic mode. By monitoring these wavelength shifts, the concentration of vitamin C in the sample can be accurately determined. This research presents a promising platform for enhanced detection of vitamin C, offering potential applications in various fields.

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Recent Advances in K-SPR Sensors for the Detection of Biomolecules and Microorganisms: A Review

Cited by 26 publications

References 100 publications

Magnetic Field Sensor Based on Magnetic Optical Surface Plasmon Resonance

Magnetic Field Sensor Based on Magnetic Optical Surface Plasmon Resonance

Optical fiber-based LSPR biosensor for enhanced dopamine detection: advancing personalized healthcare

Optical sensing of vitamin C concentrations: a novel approach with etched fiber-based plasmon sensor

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