Recent advances in living cell nucleic acid probes based on nanomaterials for early cancer diagnosis

Liu, Xuyao; Shi, Qi; Qi, Peng; Wang, Ziming; Zhang, Tongyue; Zhang, Sijia; Wu, Jiayan; Guo, Zhaopei; Chen, Jie; Zhang, Qiang

doi:10.1016/j.ajps.2024.100910

Asian Journal of Pharmaceutical Sciences

2024

DOI: 10.1016/j.ajps.2024.100910

|View full text |Cite

Recent advances in living cell nucleic acid probes based on nanomaterials for early cancer diagnosis

Xuyao Liu,

Qi Shi,

Peng Qi

et al.

Help me understand this report

Search citation statements

Order By: Relevance

Paper Sections

Select...

Citation Types

Supporting

Mentioning

Contrasting

Year Published

2024

Publication Types

Select...

Article2

Relationship

Self Cite0

Independent2

Authors

Journals

Cited by 2 publications

References 165 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

Ag₂S quantum dot-based magnetic resonance/fluorescence dual-mode imaging nanoprobes for tumor diagnosis

Zou,

Chen,

et al. 2024

Biomater. Sci.

View full text Add to dashboard Cite

show abstract

Ag₂S quantum dot-based magnetic resonance/fluorescence dual-mode imaging nanoprobes for tumor diagnosis

Zou,

Chen,

et al. 2024

Biomater. Sci.

View full text Add to dashboard Cite

show abstract

Au@CuS Nanoshells for Surface-Enhanced Raman Scattering Image-Guided Tumor Photothermal Therapy with Accelerated Hepatobiliary Excretion

Zhang,

Yu,

Sun

et al. 2024

Pharmaceutics

View full text Add to dashboard Cite

Gold-based nanoparticles for surface-enhanced Raman scattering (SERS) imaging show great potential for precise tumor detection and photothermal therapy (PTT). However, the metabolizability of gold nanoparticles (Au NPs) raises big concerns. Herein, we designed a core-shelled nanostructure of copper sulfide (CuS)-coated Au NPs with surface pegylation (PEG-Au@CuS NSs). The excreted Au in the gallbladders at 1 h and 4 h in mice injected with PEG-Au@CuS NSs was 8.2- and 19.1-fold of that with the pegylated Au NPs (PEG-AuNPs) of the same Au particle size, respectively. By loading the Raman reporter 3,3′-Diethylthiatricarbocyanine iodide (DTTC) in the core–shell junction of PEG-Au@CuS NSs, the PEG-Au-DTTC@CuS NSs exhibited the Raman signal-to-noise (S/N) ratio of 4.01 after 24 h of intravenous (IV) injection in the mice bearing an orthotopic CT26-Luc colon tumor. By contrast, the DTTC-coated PEG-AuNPs (PEG-Au-DTTC NPs) achieved an S/N ratio of 2.71. Moreover, PEG-Au-DTTC@CuS NSs exhibited an increased photothermal conversion effect compared with PEG-Au-DTTC NPs excited with an 808-nm laser. PEG-Au-DTTC@CuS NSs enabled intraoperative SERS image-guided photothermal therapy for a complete cure of the colon tumor-bearing mice. Our data demonstrated that the PEG-Au-DTTC@CuS NSs are promising intraoperative Raman image-guided theranostic nanoplatform with enhanced hepatobiliary excretion.

show abstract

scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.

Contact Info

customersupport@researchsolutions.com

10624 S. Eastern Ave., Ste. A-614

Henderson, NV 89052, USA

This site is protected by reCAPTCHA and the Google Privacy Policy and Terms of Service apply.

Blog Terms and Conditions API Terms Privacy Policy Contact Cookie Preferences Do Not Sell or Share My Personal Information

Made with 💙 for researchers

Part of the Research Solutions Family.

Recent advances in living cell nucleic acid probes based on nanomaterials for early cancer diagnosis

Cited by 2 publications

References 165 publications

Ag₂S quantum dot-based magnetic resonance/fluorescence dual-mode imaging nanoprobes for tumor diagnosis

Ag₂S quantum dot-based magnetic resonance/fluorescence dual-mode imaging nanoprobes for tumor diagnosis

Au@CuS Nanoshells for Surface-Enhanced Raman Scattering Image-Guided Tumor Photothermal Therapy with Accelerated Hepatobiliary Excretion

Contact Info

Product

Resources

About

Recent advances in living cell nucleic acid probes based on nanomaterials for early cancer diagnosis

Cited by 2 publications

References 165 publications

Ag2S quantum dot-based magnetic resonance/fluorescence dual-mode imaging nanoprobes for tumor diagnosis

Ag2S quantum dot-based magnetic resonance/fluorescence dual-mode imaging nanoprobes for tumor diagnosis

Au@CuS Nanoshells for Surface-Enhanced Raman Scattering Image-Guided Tumor Photothermal Therapy with Accelerated Hepatobiliary Excretion

Contact Info

Product

Resources

About

Ag₂S quantum dot-based magnetic resonance/fluorescence dual-mode imaging nanoprobes for tumor diagnosis

Ag₂S quantum dot-based magnetic resonance/fluorescence dual-mode imaging nanoprobes for tumor diagnosis