Recent advances in the management of postmenopausal women with non-atypical endometrial hyperplasia

Ren, Hai; Zhang, Y; Duan, Hua

doi:10.1080/13697137.2023.2226316

Cited by 3 publications

(3 citation statements)

References 80 publications

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“…A menudo, en mujeres posmenopáusicas con hiperplasia endometrial, se opta por intervenciones quirúrgicas, incluida la histerectomía. No obstante, cómo abordar a las mujeres posmenopáusicas con hiperplasia endometrial es un tema que aún genera debate en la comunidad médica (16).…”

Section: Indicaciones Clínicas Para Una Histerectomíaunclassified

Complicaciones intra y post operatorias de las histerectomías: laparoscópica, abdominal y vaginal en mujeres adultas.

Guarnizo-Orellana,

Guerrero-Cevallos

2023

MQRInvestigar

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Objetivo: describir las complicaciones intra y post operatorias de las histerectomías: laparoscópica, abdominal y vaginal en mujeres adultas. Metodología: se realizó una revisión bibliográfica basada en criterios de selección que abarcaron artículos publicados desde 2018 hasta la fecha. Las fuentes consultadas incluyeron bases de datos reconocidas como Scopus, Scielo, JAMA, Redalyc, Pubmed, ScienceDirect y SpringerLink. Se emplearon términos de búsqueda como "Histerectomía", "Hysterectomy", "Histerectomía Vaginal", "Colpohisterectomía" y "Vaginal Hysterectomy". A partir de esta búsqueda, se seleccionaron 44 estudios que sirvieron como base para la investigación. Resultados: la histerectomía es una cirugía común en mujeres, cuyas indicaciones dependen del tipo de procedimiento y la condición clínica del paciente. Esta intervención puede presentar complicaciones, las cuales están influenciadas por diversos factores, entre ellos el IMC del paciente y la experiencia del cirujano. Existen diferentes técnicas de histerectomía, cada una con su propio perfil de complicaciones. Es esencial que, al seleccionar la técnica, se considere la situación clínica del paciente y la experiencia del cirujano para minimizar los riesgos asociados. Conclusiones: la histerectomía es una intervención esencial en la salud ginecológica, pero no está exenta de riesgos. La elección de la técnica quirúrgica y la experiencia del cirujano son determinantes en el resultado postoperatorio. Es imperativo que los profesionales de la salud estén bien informados y capacitados para seleccionar el procedimiento adecuado, adaptado a las necesidades y condiciones de cada paciente, con el objetivo de garantizar una recuperación segura y eficaz.

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Section: Indicaciones Clínicas Para Una Histerectomíaunclassified

Complicaciones intra y post operatorias de las histerectomías: laparoscópica, abdominal y vaginal en mujeres adultas.

Guarnizo-Orellana,

Guerrero-Cevallos

2023

MQRInvestigar

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“…EH could be further classified into two subtypes during its development: endometrial hyperplasia without atypia (EHA) and endometrial atypical hyperplasia (EAH). EHA is a benign disease without significant somatic genetic changes, along with a significant risk of transforming EC and persistent EH . EAH is regarded as a precancerous condition leading to EC, whose pathological progression is complex and exhibits a multiplicity over time and spatial distribution .…”

Section: Introductionmentioning

confidence: 99%

“…EHA is a benign disease without significant somatic genetic changes, along with a significant risk of transforming EC and persistent EH. 4 EAH is regarded as a precancerous condition leading to EC, 5 whose pathological progression is complex and exhibits a multiplicity over time and spatial distribution. 6 It is widely recognized that women with EAH have a higher risk of progressing to EC compared to those with EHA.…”

Section: Introductionmentioning

confidence: 99%

Integrative Analysis of Multi-Omic Data for the Characteristics of Endometrial Cancer

Li,

Ruan,

Song

et al. 2024

ACS Omega

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Endometrial cancer (EC) is a frequently diagnosed gynecologic cancer. Identifying reliable prognostic genes for predicting EC onset is crucial for reducing patient morbidity and mortality. Here, a comprehensive strategy with transcriptomic and proteomic data was performed to measure EC's characteristics. Based on the publicly available RNA-seq data, death-associated protein kinase 3, recombination signal-binding protein for the immunoglobulin kappa J region, and myosin light chain 9 were screened out as potential biomarkers that affect the EC patients' prognosis. A linear model was further constructed by multivariate Cox regression for the prediction of the risk of being malignant. From further integrative analysis, exosomes were found to have a highly enriched role that might participate in EC occurrence. The findings were validated by qRT-polymerase chain reaction (PCR) and western blotting. Collectively, we constructed a prognosticgene-based model for EC prediction and found that exosomes participate in EC incidents, revealing significantly promising support for the diagnosis of EC.

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Postmenopausal endometrial non-benign lesion risk classification through a clinical parameter-based machine learning model

Lai,

Rao,

Tian

et al. 2024

Computers in Biology and Medicine

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Recent advances in the management of postmenopausal women with non-atypical endometrial hyperplasia

Cited by 3 publications

References 80 publications

Complicaciones intra y post operatorias de las histerectomías: laparoscópica, abdominal y vaginal en mujeres adultas.

Complicaciones intra y post operatorias de las histerectomías: laparoscópica, abdominal y vaginal en mujeres adultas.

Integrative Analysis of Multi-Omic Data for the Characteristics of Endometrial Cancer

Postmenopausal endometrial non-benign lesion risk classification through a clinical parameter-based machine learning model

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