Recent Advances in the Synthesis and Application of Chiral Ionic Liquids

Abstract

The review is intended to summarize the research field of chiral ionic liquids over the last two years. Alongside the syntheses of new chiral ionic liquids, their applications are covered. Furthermore, the synthesis of task-specific ionic liquids, also known as functionalized chiral ionic liquids, and their applications are summarized.

Sustainable sonochemical synthesis of N‐protected piperazine‐propargylamines using ionic liquids and CuI

“…1a,b As environmental concerns rise, ILs are emerging as increasingly attractive replacements for traditional solvents due to their eco-friendly properties. 2 ILs have garnered immense attention in the realm of catalysis, extending their reach to diverse applications including energy production, 3 biocatalysts, 4a,b selective metal ion extraction, 5a,b carbon dioxide capture, 6 biomass transformation, 7a,b electrochemical window, 8 thermal stability, 9 and the synthesis of new ion conductive materials. 10 ILs have exceptional thermal stability and are truly non-volatile and non-flammable even at high temperatures due to their unique and tuneable features.…”

“…Driven by the need to minimize waste, synthetic chemists are pioneering environmentally friendly methods using non‐toxic catalysts, eco‐compatible solvents, and promoting solvent recyclability 1a,b . As environmental concerns rise, ILs are emerging as increasingly attractive replacements for traditional solvents due to their eco‐friendly properties 2 …”

Liquid–Liquid Equilibrium Measurement for the Separation of n-Propanol + n-Propyl Acetate Using Imidazolium-Based Ionic Liquids with Different Anions at T = 303.15 K

“…In recent years, ionic liquids (ILs), as a new generation of green solvents, have attracted widespread attention in the field of liquid–liquid extraction because of their low volatility, outstanding chemical and thermal stability, wide liquid temperature range, and designability − and have gradually become sustainable alternatives to conventional organic solvents. Till date, many researchers have explored the separation of (alcohol + ester) azeotropic systems by liquid–liquid extraction employing ILs as extractants.…”

Straightforward synthesis of chiral sulfonate‐based ionic liquids from amino alcohols for chiral recognition

“…2 Chiral ionic liquids (CILs), which are composed of chiral cations and/or anions, offer an additional advantage as chiral solvents in asymmetric reactions, as chiral catalysts, or as chiral solvating agents. [3][4][5][6][7][8] Chiral solvating agents are important tools in the determination of enantiomeric ratios of chiral compounds, especially in NMR spectroscopy. The use of CILs as solvating agents has advantages over traditional chiral solvents, including high solubility and high selectivity.…”