Recent advances in the synthesis of thienoindole analogs and their diverse applications

Abstract

Synthesis of thienoindoles via easy and atom economical approaches followed by their potent applications.

Emerging trends in the development and applications of triazine-based covalent organic polymers: a comprehensive review

“…112 Their efficacy lies in their ability to yield the desired products in one pot and one step, making them an easy and atom economical approach. 113 MCRs involve more than two reactants, which selectively react with each other to give the desired product. Various bioactive heterocyclic compounds and drug molecules have been developed using these environmentally benevolent reactions.…”

A general approach to construct selenopheno[3,2-b]indole-cored molecules using Fischer indolization

“…In support of this, thienoindole ring systems, sulfur-containing analogs of selenophenoindoles, were widely used as the basis of biologically active compounds 15 and organic semiconductors. 16 However, in contrast to thienoindoles, the methods for the synthesis of selenophenoindoles are very limited in the literature. Thus, two approaches were recently suggested for the synthesis of selenopheno[2,3- b ]indoles, including the electrophilic cyclization of 3-(arylethynyl)indoles 1 with in situ generated SeCl 2 to form 2-aryl-substituted derivatives 2 17 (Scheme 1a) and IBr-promoted three-component reaction of indoles 3 with acetophenones or some hetaryl methyl ketones and selenium powder to form 3-(hetero)aryl-substituted derivatives 4 (Scheme 1b).…”