Recent Advances in the Synthesis of Five-Membered Cyclic Carbonates and Carbamates from Allylic or Propargylic Substrates and CO2

Abstract

The organic carbamates and carbonates are highly desirable compounds that have found a wide range of applications in drug design, medicinal chemistry, material science, and the polymer industry. The development of new catalytic carbonate and carbamate forming reactions, which employ carbon dioxide as a cheap, green, abundant, and easily available reagent, would thus represent an ideal substitution for existing methods. In this review, the advancements in the catalytic conversion of allylic and propargylic alcohols and amines to corresponding five-membered cyclic carbonates and carbamates are summarized. Both the metal- and the organocatalyzed methods are reviewed, as well as the proposed mechanisms and key intermediates of the illustrated carbonate and carbamate forming reactions.

Recent Advances in the Fixation of CO2 into Quinazoline and Benzimidazole

“…It is evident that, while several reviews in the past decade (2015–2023) cover CO 2 conversion to specific product classes like cyclic carbonates, − oxazolidinones, − polymers, − metal–organic frameworks, − carbamates and heterocycles, − there is still a lack of a focused and up-to-date review specifically on catalytic pathways for synthesizing the pharmaceutically important N-heterocyclic compounds benzimidazole and quinazoline from CO 2 . − …”