Recent Advances in the Synthesis of Corroles and Core-Modified Corroles

Abstract

The aim of this review is to highlight recent progress in the synthetic methodologies leading to corroles and core-modified corroles. Emphasis is put on corroles with meso substituents.

Developments in the metal chemistry of N-confused porphyrin

“…If the reaction is done in the presence of K 2 CO 3 /dibenzo [18]-crown-6, the externally coordinated form is favored. The absorption spectra of Ni(21-ethoxymethyl NCTPP) is similar to the internally methylated derivative with a Soret at 429 nm and an undefined Q band structure, while the Ni(2N-ethoxymethyl NCTPP) is similar to the externally methylated form (Soret at 427 and 460 nm, Q bands at 533, 560, 593, 649, 720 and 789 nm).…”

“…1b-d) [11] where the meso carbons are rearranged to form new macrocycle structures. The analogs of porphyrin are more diverse, and range from contracted , homophyrins (f), thiaporphyrins (g, X = S), and oxaporphyrins (g, X = O) [11][12][13][14][15][16][17][18][19][20][21][22][23][24][25][26][27].…”

“…1e) [12][13][14][15][16][17][18][19], to expanded systems like the homophyrins (Fig. 1f) [20], and heteroatom substituted macrocycles, such as thiaporphyrins [21][22][23][24] and oxaporphyrins [25][26][27] (Fig.…”

Cellular uptake and anticancer activity of carboxylated gallium corroles

“…Corroles have received a great deal of attention in recent years (10)(11)(12)(13), owing to dramatic advances in methods for their preparation (14)(15)(16)(17)(18)(19)(20)(21)(22)(23)(24)(25)(26)(27)(28)(29)(30)(31). Of interest here is a gallium(III) complex, 1 [Ga(tpfc)] (32)(33)(34)(35), where tpfc represents the trianion of 5,10,15-tris(pentafluorophenyl)corrole [H 3 (tpfc)].…”

The simple synthesis of stable A 3 - and trans -A 2 B-molybdenum(V) corrolates

“…Our on-going studies in oxygen activation area prompted us to search ligands which are much better suited for stabilization of molybdenum(V) complexes than porphyrin. Therefore we turned to newly emerged area of corroles.Corroles [9,10] are aromatic tetrapyrrole macrocycles bearing a direct pyrrole-pyrrole link and only in recent years has this area of research begun to attract attention as an independent rapidly evolving field. Interest in corroles was induced by the discovery of their remarkable ability to stabilize higher oxidation states of metals [11] and by significant synthetic developments made during the last four years [11][12][13].…”