Recent advances of green pretreatment techniques for quality control of natural products

Abstract

A few advancing technologies for natural product analysis have been widely proposed, which focus on decreasing energy consumption and developing an environmentally sustainable manner. These green sample pretreatment and analysis methods following the green Analytical Chemistry (GAC) criteria have the advantage of improving the strategy of chemical analyses, promoting sustainable development to analytical laboratories, and reducing the negative effects of analysis experiments on the environment. A few minimized extraction methodologies have been proposed for replacing the traditional methods in the quality evaluation of natural products, mainly including solid‐phase microextraction (SPME) and liquid phase microextraction (LPME). These procedures not only have no need for large numbers of samples and toxic reagent, but also spend a small amount of extraction and analytical time. This overview aims to list out the main green strategies on the application of quality evaluation and control for natural products in the past 3 years.

Recent Advances in Analytical Techniques for Antidepressants Determination in Complex Biological Matrices: A Review

“…69 Eliminating interfering species, extracting analytes, and increasing the concentration of the analyte to improve the final signal are the main objectives of the pre-treatment procedure. 70 We carried out an in-depth review of the different techniques, particularly recent trends, employed in laboratories for antidepressant extraction from various biological matrices.…”

Ethyl Acetate Extract of Dracocephalum heterophyllum Benth Ameliorates Nonalcoholic Steatohepatitis and Fibrosis via Regulating Bile Acid Metabolism, Oxidative Stress and Inhibiting Inflammation

“…ESI-MS spectra were obtained on the Agilent 6500 series Q-TOF mass spectrometer. Using deuterated methanol as a solvent, the 1 H and 13 C nuclear magnetic resonance (NMR) spectroscopic data were recorded on the Bruker Avance NMR spectrometer at 600 MHz. Multimode Microplate Reader was purchased from Molecular Devices (Shanghai, China), while the BioMajesty ® JCA-BM6010/C was supplied by the Sysmex (Wuxi, China).…”

“…The comparison with the ch matogram of the crude extract (Figure 9A) demonstrated that Fr31 was indeed the m functional compound present in the ethyl acetate extraction of D. heterophyllum. Its str ture was further studied by ESI-MS, 1 H, and 13 C NMR spectral analyses and data w documented and identified in comparison with the present information in the literatu Below, we list all spectra of the original spectra records, while the raw spectra are sho in the supporting materials (Figures S1-S3). Our results proved that the key compon isolated from the ethyl acetate extraction of D. heterophyllum was the rosmarinic acid.…”

“…The following supporting information can be downloaded at: https:// www.mdpi.com/article/10.3390/separations9100273/s1, Figure S1: ESI mass spectrum of rosmarinic acid; Figure S2: 1 H NMR Spectrum (600 MHz) of rosmarinic acid (in MeOH-d 4 ); Figure S3: 13 C NMR Spectrum (151 MHz) of rosmarinic acid (in MeOH-d 4 ).…”

“…NASHrelated clinical drugs result in the reduction of hepatocyte steatosis and the activation of hepatic stellate cells, which then inhibit the extracellular matrix synthesis [5,6]. Both inflammation and oxidative stress, as pivotal initiating and promoting factors for NASH and liver fibrosis, can certainly be selected as significant targets for the treatment [7,8], as metabolites produced by organisms through the evolutionary process of the survival of the fittest, natural products (NPs) have long been an indispensable resource for the development of new therapies [9][10][11][12][13].…”