Recent advances on developing 3rd generation enzyme electrode for biosensor applications

Das, Priyanki; Das, Madhuri; Chinnadayyala, Somasekhar R.; Singha, Irom Manoj; Goswami, Pranab

doi:10.1016/j.bios.2015.12.055

Cited by 210 publications

(100 citation statements)

References 136 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Also, these materials provide a close gap between the redox active group of an enzyme and the electrode surface to accomplish the direct electron transfer (DET) for the fabrication of third generation enzyme‐based biosensors (TGB) . TGB have attracted considerable attention due to their mediator‐free design . Also, by operating at negative voltage values, TGB can overcome the interference issue along with providing more accurate analyte determination .…”

Section: Introductionmentioning

confidence: 66%

Tannic Acid Modified Electrochemical Biosensor for Glucose Sensing Based on Direct Electrochemistry

Çakıroğlu

Özacar

2017

Electroanalysis

View full text Add to dashboard Cite

A novel glucose biosensor was constructed through the immobilization of glucose oxidase (GOx) on gold nanoparticles (Au NPs) deposited, and chemically reduced graphene oxide (rGO) nanocomposite. In the synthesis, tannic acid (TA) was used for the reduction of both graphene oxide, and Au3+ to rGO, and Au NPs, respectively. Also, by harnessing the π‐π interaction between graphene oxide and TA, and protein‐TA interaction, a novel nanocomposite for the fabrication of a third generation biosensor was successfully constructed. Upon the oxidation of TA to quinone, which is easily reducible at the negative potential range, enhanced electron transfer was obtained. The cyclic voltammetry (CV) results demonstrated a pair of well‐defined and quasi‐reversible redox peaks of active site molecule of GOx. The biosensor exhibited a linear response to glucose concentrations varying from 2 to 10 mM with a sensitivity of 18.73 mA mM−1 cm−2. The fabricated biosensor was used for the determination of glucose in beverages.

show abstract

Section: Introductionmentioning

confidence: 66%

Tannic Acid Modified Electrochemical Biosensor for Glucose Sensing Based on Direct Electrochemistry

Çakıroğlu

Özacar

2017

Electroanalysis

View full text Add to dashboard Cite

show abstract

“…These biosensors combine electrochemical transduction with recognition reactions catalyzed by immobilized enzymes [60,61]. Numerous MIPs mimic enzyme active centers, exhibiting selective catalytic properties [62,63].…”

Section: What If the Template Is Too Fragile?mentioning

confidence: 99%

Artificial Biosensors: How Can Molecular Imprinting Mimic Biorecognition?

Cieplak

Kutner

2016

Trends in Biotechnology

207

113

View full text Add to dashboard Cite

“…The first generation is based on measuring peroxide formation and necessitates oxygen, the second uses an additional mediator which transports electrons from the enzyme active site to the electrode, and the third is based on direct electron transfer (DET) between active site of enzyme and the electrode. 33 A major focus of microneedle-based sensor research has relied on first and second-generation type biosensing principles and the largest number of publications for the same have been recorded since the past two decades. Herein we have discussed and reported in detail about the recent trends in enzymatic CGM microneedle glucose sensors.…”

Section: Enzymatic Microneedle Glucose Sensingmentioning

confidence: 99%

Editors' Choice—Review—In Vivo and In Vitro Microneedle Based Enzymatic and Non-Enzymatic Continuous Glucose Monitoring Biosensors

Chinnadayyala

Park

Cho

2018

ECS J. Solid State Sci. Technol.

Self Cite

View full text Add to dashboard Cite

Microneedles have emerged for transdermal monitoring of biomarkers, which are a miniaturized replica of hypodermic needles with length-scales of hundreds of micrometers, with a goal to achieve time-sensitive clinical information for routine point-of-care health monitoring. Transdermal biosensing via microneedles offers remarkable opportunities for moving biosensing technologies from research laboratories to real-field applications and enables development of easy-to-use point-of-care microdevices, minimally invasive, and with minimal-training features that are very attractive for both developed and emerging countries. This would eliminate the need for blood extraction using hypodermic needles and in turn, reduce the related problems such as infections in the patients, sample contaminations, and analysis artifacts. In this review, we provide a general overview of recent progress in microneedlebased sensing research, including: (a) in-vivo microneedle diagnostic systems for glucose monitoring with an emphasis on sensor construction and general health monitoring (b) in-vitro use of microneedle sensors. The main objective of the review is to provide a thorough and critical analysis of recent advances and developments in microneedle research field and to bridge the gap between microneedles and biosensors.

show abstract

Recent advances on developing 3rd generation enzyme electrode for biosensor applications

Cited by 210 publications

References 136 publications

Tannic Acid Modified Electrochemical Biosensor for Glucose Sensing Based on Direct Electrochemistry

Tannic Acid Modified Electrochemical Biosensor for Glucose Sensing Based on Direct Electrochemistry

Artificial Biosensors: How Can Molecular Imprinting Mimic Biorecognition?

Editors' Choice—Review—In Vivo and In Vitro Microneedle Based Enzymatic and Non-Enzymatic Continuous Glucose Monitoring Biosensors

Contact Info

Product

Resources

About