2022
DOI: 10.1039/d2ma00814a
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Recent advances on drug delivery nanoplatforms for the treatment of autoimmune inflammatory diseases

Abstract: As one of the current research hotspots, drug release nanoplatforms have great potential in the treatment of autoimmune inflammatory diseases. At present, most of the drugs used in clinic do...

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Cited by 11 publications
(6 citation statements)
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“…Such NPs can release therapeutic components in response to a specific stimulus in the environment. 53,54 Things like magnetism, light, sound, a certain range of pH, oxidative stress, enzymes. The clinical application of nanotechnology is mainly reflected in diagnosis and treatment.…”
Section: Strategies Of Targeted Nps In the Treatment Of Ismentioning
confidence: 99%
“…Such NPs can release therapeutic components in response to a specific stimulus in the environment. 53,54 Things like magnetism, light, sound, a certain range of pH, oxidative stress, enzymes. The clinical application of nanotechnology is mainly reflected in diagnosis and treatment.…”
Section: Strategies Of Targeted Nps In the Treatment Of Ismentioning
confidence: 99%
“…12A), and Van, which can form an intricate network of hydrogen bonds with the D-Ala-D-Ala region of lipid II in S. aureus, will interfere with the maturation process of the peptidoglycan layer. 68,69 This will further weaken the cell wall of the bacteria, and render the cells susceptible to lysis due to alterations in osmotic pressure. 70 Gram-negative bacteria, such as E. coli, are protected by the outer lipopolysaccharide membrane that is impermeable to large biomolecules, such as Van, and hydrophobic compounds from the environment (Fig.…”
Section: Targeted Antibacterial Effect Of Van-loaded Gel/n-ha Microsp...mentioning
confidence: 99%
“…OPNPs-based therapeutic approaches are thought to be promising options for tumor diagnosis and therapy, but one of the main obstacles is targeted delivery to tumors . The accumulation of OPNPs in tumor tissue is facilitated by the enhanced permeability and retention (EPR) effect, which arises from the leaky vasculature and poor lymphatic drainage of tumors. , Moreover, OPNPs can be modified to precisely bind to antigens on the surface of cancer cells, which enhances tumor targeting. To improve the efficacy of PDT for PCa, it is crucial to attach PSs to specific ligands or surface receptors of PCa, thereby achieving selective binding and efficient PDT.…”
Section: Opnps-mediated Pdt For Prostate Cancermentioning
confidence: 99%