2020
DOI: 10.3390/polym12061386
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Recent Advances on Nanofiber Fabrications: Unconventional State-of-the-Art Spinning Techniques

Abstract: In this review, we describe recent relevant advances in the fabrication of polymeric nanofibers to address challenges in conventional approaches such as electrospinning, namely low throughput and productivity with low size uniformity, assembly with a regulated structure and even architecture, and location with desired alignments and orientations. The efforts discussed have mainly been devoted to realize novel apparatus designed to resolve individual issues that have arisen, i.e., eliminating ejection tips of s… Show more

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Cited by 59 publications
(40 citation statements)
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References 100 publications
(119 reference statements)
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“…Thus, it is expected that three pumps must be the prerequisite for quantitatively driving the three different working fluids to the core, middle, and outer layer inlets of the spinneret at the same time. Certainly, other apparatuses can be added or combined with the electrospinning systems to expand their capability of creating novel nanomaterials [ 59 , 60 , 61 , 62 , 63 , 64 , 65 , 66 , 67 ].…”
Section: Resultsmentioning
confidence: 99%
“…Thus, it is expected that three pumps must be the prerequisite for quantitatively driving the three different working fluids to the core, middle, and outer layer inlets of the spinneret at the same time. Certainly, other apparatuses can be added or combined with the electrospinning systems to expand their capability of creating novel nanomaterials [ 59 , 60 , 61 , 62 , 63 , 64 , 65 , 66 , 67 ].…”
Section: Resultsmentioning
confidence: 99%
“…Furthermore, mechanical properties appear to be crucial for tissue engineering. A reactive electrospinning approach might be helpful in attaining the required mechanical properties as it helps to safely and successfully upload different therapeutic hormones and drug moieties actively and stably [ 100 , 101 ].…”
Section: Drug Delivery Options For Cardiovascular Interventions: Hmentioning
confidence: 99%
“…This technique consents the control of fiber diameter and alignment, but presents some limitations in the formation of thicker constructs and consequently in mechanical strength. Recent advances in fabrication of nanofibers using novel apparatus of electrospinning system could bring addressing specific issues, in order to manufacturing high-quality 3D scaffolds [113]. Additive manufacturing, including selective laser sintering and bioprinting, consents to produce a 3D construct on the basis of a predefined CAD drawing.…”
Section: Challenges and Future Perspectivesmentioning
confidence: 99%