“…If a prolonged period of the inflammation phase unfolds, then an acute wound may be classified as a chronic wound, which often experience a postponed and incomplete healing process (Jones et al, 2018, Maaz Arif et al, 2021. Wound healing can be delayed by the presence of intrinsic and extrinsic factors including the lack of nutrition, pathogenic infections, co-morbidities, medications, or inappropriate wound dressing selection or management (He et al, 2022, Nosrati et al, 2021. When the defensive skin integrity is compromised in an open wound, it allows the invasion of pathogenic microorganisms, causing local infections or even sepsis (Duan et al, 2022, Chelkeba andMelaku, 2021).…”