Recent approaches for enhanced production of microbial polyhydroxybutyrate: Preparation of biocomposites and applications

Evaluation and Characterization of Ultrathin Poly(3-hydroxybutyrate) Fibers Loaded with Tetraphenylporphyrin and Its Complexes with Fe(III) and Sn(IV)

“…The widespread employment of nanotechnology in modern medicine, the transition from traditional macro- and micro- to submicron and nanoscale medication forms (MF), as well as the implementation of ultrafine implants and diagnostic systems, cause the scientific community to pay close attention to bio-based polymer materials that are completely decomposed in the living systems without the formation of toxic products. Poly(3-hydroxybutyrate) (PHB) as a basic representative of polyhydroxyalkanoates’ family (PHA) is such bacterial biodegradable and biocompatible polymer with great commercial perspectives and high sustainability [ 1 , 2 , 3 ]. PHB micro/nano fibers have been fabricated by electrospinning (ES), which is well-developed for creating nanoscale polymer carriers with adjustable morphology and properties [ 4 , 5 ] The ES technique provides the design of nonwoven fibrous membranes (mats) with a large inherent surface-to-volume ratio [ 6 ] that is extremely important for biomedical, packaging, and environmental applications.…”

Modification of Cellulose Micro- and Nanomaterials to Improve Properties of Aliphatic Polyesters/Cellulose Composites: A Review

“…Poly(3-hydroxybutyrate) (P3HB, PHB) is a thermoplastic, biodegradable, semicrystalline, linear microbial aliphatic polyester [ 5 , 8 , 79 , 87 ]. Biosynthesis in cells of natural/transgenic plants and bacterial fermentation, including the use of genetically modified microorganisms, are the main ways for the production of P3HB [ 8 , 79 , 87 ].…”

“…Poly(3-hydroxybutyrate) (P3HB, PHB) is a thermoplastic, biodegradable, semicrystalline, linear microbial aliphatic polyester [ 5 , 8 , 79 , 87 ]. Biosynthesis in cells of natural/transgenic plants and bacterial fermentation, including the use of genetically modified microorganisms, are the main ways for the production of P3HB [ 8 , 79 , 87 ]. In particular, P3HB is produced by prokaryotic microorganisms from sugar-based media (agricultural industrial wastes, hydrolysates of some wood) and other carbon sources in the form of inclusion bodies, which serve as intracellular bacterial depots storing carbon and energy [ 5 , 79 , 87 ].…”

“…Biosynthesis in cells of natural/transgenic plants and bacterial fermentation, including the use of genetically modified microorganisms, are the main ways for the production of P3HB [ 8 , 79 , 87 ]. In particular, P3HB is produced by prokaryotic microorganisms from sugar-based media (agricultural industrial wastes, hydrolysates of some wood) and other carbon sources in the form of inclusion bodies, which serve as intracellular bacterial depots storing carbon and energy [ 5 , 79 , 87 ]. Microorganisms may accumulate up to 40–50% of P3HB from the dry-cell mass, and in the case of Alcaligenes eutrophus the accumulation may reach up to 96% of the dry cell mass [ 87 ].…”

“…In particular, P3HB is produced by prokaryotic microorganisms from sugar-based media (agricultural industrial wastes, hydrolysates of some wood) and other carbon sources in the form of inclusion bodies, which serve as intracellular bacterial depots storing carbon and energy [ 5 , 79 , 87 ]. Microorganisms may accumulate up to 40–50% of P3HB from the dry-cell mass, and in the case of Alcaligenes eutrophus the accumulation may reach up to 96% of the dry cell mass [ 87 ]. Depending on the conditions and isolation forms, the resulting P3HB can have different characteristics (molecular weight, crystallinity, mechanical properties and ability to biodegrade) [ 8 , 79 ].…”