Recent cancer survival in <scp>G</scp>ermany: An analysis of common and less common cancers

Jansen, Lina; Castro, Felipe A.; Gondos, Ádám; Krilavičiūtė, Agnė; Barnes, Benjamin; Eberle, Andrea; Emrich, Katharina; Hentschel, Stefan; Holleczek, Bernd; Katalinic, Alexander; Brenner, Hermann

doi:10.1002/ijc.29316

Cited by 70 publications

(53 citation statements)

References 36 publications

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“…The improvement in the 5- and 10-year RS by about 6 percent units can also be seen in other German population cohorts [17]. These authors also conclude that the survival improvement might be attributable to the shift to more localised tumours due to the increased use of PSA screening.…”

Section: Discussionsupporting

confidence: 61%

Changes in Prognostic and Therapeutic Parameters in Prostate Cancer from an Epidemiological View over 20 Years

et al. 2015

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Background: The study objective was to examine changes in prognosis and treatment of prostate cancer patients over 20 years and to evaluate their impact on survival. Patients and Methods: 38,861 prostate cancer patients diagnosed between 1990 and 2010 and living in the catchment area of the Munich Cancer Registry were analysed. Results: Pre-therapeutic prostate-specific antigen (PSA) testing increased substantially in the early 1990s. A shift from capsule-exceeding tumours to capsule-limited tumours also took place especially in the 1990s. The proportion of radical prostatectomy increased continuously over the last 20 years from 20% to almost 50% whereas hormone therapy decreased from 55% to 18%. Radiation therapy and transurethral resection of the prostate increased slightly from about 5% to 10%. The 5- and 10-year relative survival rates increased from 92% to 97% and from 86% to 92%, respectively. Conclusions: 2 reasons may account for the rise in survival rates over 20 years: First, the establishment of widely used PSA testing resulted in a shift towards more favourable T categories due to the detection of many additional small tumours as well as the noticeable change in initial treatment strategy towards more radical prostatectomies. The second factor that likely increased survival was improvements in the therapies themselves.

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Section: Discussionsupporting

confidence: 61%

Changes in Prognostic and Therapeutic Parameters in Prostate Cancer from an Epidemiological View over 20 Years

et al. 2015

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“…Five-year relative survival increased from 39.9% in patients diagnosed 2002–2004 to 47.9% in 2008–2010 in a study from 11 population-based cancer registries in Germany (33). Five-year relative survival increased from 45.7% to 49.9% to 55.7% for patients diagnosed in the calendar periods 1988–1996, 1997–2005 and 2006–2009, respectively in a study from the Modena Cancer Registry in Italy (34).…”

Section: Resultsmentioning

confidence: 99%

Rapidly changing myeloma epidemiology in the general population: Increased incidence, older patients, and longer survival

Turesson

Björkholm

Blimark

et al. 2018

European J of Haematology

130

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The incidence of multiple myeloma is characterized by a steep increase with advancing age. Dramatic improvements in survival have been reported in clinical trials; however, elderly patients are generally underrepresented in these. The aims of this study are to review patterns of incidence and survival in multiple myeloma in the general population. We searched PubMed for population-based studies on trends in incidence and survival published between January 1, 2000 and June 30, 2017 and based on regional or national cancer registries and report the following results of the review. The age-adjusted incidence of multiple myeloma has increased during the second half of the twentieth century in some countries but remained stable in areas with high case ascertainment and access to universal medical care. The crude incidence is increasing globally due to an aging population. Survival rates have improved, and 5-year relative survival rates are now around 50% and over 60% in patients 65-70 years or younger. Preliminary data suggest a 3-fold increase in the prevalence of multiple myeloma. We conclude that the number of multiple myeloma patients is increasing in the general population due to (i) aging populations and (ii) more patients living longer due to modern drugs.

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“…With the steady progress in cancer treatment and survival,1,2 as well as an aging population, cancer prevalence is increasing. Some cancers (eg, colorectal cancer) have shown improvements in 5-year survival, while other high-prevalence cancers (eg, lung cancer) have not.…”

Section: Introductionmentioning

confidence: 99%

Complexity of care and strategies of self-management in patients with colorectal cancer

Ose¹,

Winkler²,

Berger³

et al. 2017

PPA

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PurposeGiven the inherent complexity of cancer care, in which personal, social, and clinical aspects accumulate and interact over time, self-management support need to become more comprehensive. This study has the following two aims: 1) to analyze and describe the complexity of individual patient situations and 2) to analyze and describe already established self-management strategies of patients to handle this complexity.MethodsA qualitative study was conducted. Ten focus groups were performed collecting perspectives of the following three user groups: patients with colorectal cancer (n=12) and representatives from support groups (n=2), physicians (n=17), and other health care professionals (HCPs; n=16). Data were analyzed using qualitative content analysis.ResultsThe results showed that cancer patients are struggling with the complexity of their individual situations characterized by the 1) “complexity of disease”, 2) “complexity of care”, and 3) “complexity of treatment-related data”. To deal with these multifaceted situations, patients have established several individual strategies. These strategies are “proactive demanding” (eg, to get support and guidance or a meaningful dialog with the doctor), “proactive behavior” (eg, preparation of visits), and “proactive data management” (eg, in terms of merging treatment-related data and to disseminate these to their health care providers).ConclusionPatients with colorectal cancer have to handle a high complexity of individual situations within treatment and care of their disease. Private and social challenges have a culminating effect. This complexity increases as patients experience a longer duration of treatment and follow-up as patients have to handle a significantly higher amount of data over time. Self-management support should focus more on the individual complexity in a patient’s life. This includes assisting patients with strategies that have already been established by themselves (like preparation of visits).

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Recent cancer survival in Germany: An analysis of common and less common cancers

Cited by 70 publications

References 36 publications

Changes in Prognostic and Therapeutic Parameters in Prostate Cancer from an Epidemiological View over 20 Years

Changes in Prognostic and Therapeutic Parameters in Prostate Cancer from an Epidemiological View over 20 Years

Rapidly changing myeloma epidemiology in the general population: Increased incidence, older patients, and longer survival

Complexity of care and strategies of self-management in patients with colorectal cancer

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