Recent concepts in feline lower urinary tract disease

Hostutler, Roger A.; Chew, Dennis J.; DiBartola, Stephen P.

doi:10.1016/j.cvsm.2004.08.006

Cited by 118 publications

(180 citation statements)

References 35 publications

Supporting

Mentioning

144

Contrasting

Unclassified

Order By: Relevance

“…Since the animals in the HRG had dyspnea and tachypnea in an attempt to compensate for the metabolic acidosis and pleural effusion, the HRG had significantly lower pCO 2 compared to LRG at 24 h. The HRG had lower HCO 3 and BE (P < 0.05) compared with the LRG at 8, 12, 24 and 48 h. This group also had lower HCO 3 and BE values than baseline at 0, 2, 8, 12 and 24h, while this was the case in the LRG only at 0 and 2 h. Even though a solution with the precursor for bicarbonate was infused, the HRG did not present stabilization of HCO 3 and BE until 24 h and 48 h respectively, probably due to consumption of bicarbonate as a result of metabolic acidosis.…”

Section: Cats Received Meloxicammentioning

confidence: 94%

“…Death may occur as a result of cardiopulmonary failure, water-electrolyte imbalance or acute renal failure [2]. Fluid therapy is the most important component involved in the stabilization of postrenal azotemia because it alleviates hyperkalemia, acidosis, and azotemia in most instances [3]. It is recommended that administration of fluids commence as soon as possible to correct the water-electrolyte balance and replace urinary losses due to dehydration and post obstructive dieresis [1,3,4].…”

mentioning

confidence: 99%

“…Fluid therapy is the most important component involved in the stabilization of postrenal azotemia because it alleviates hyperkalemia, acidosis, and azotemia in most instances [3]. It is recommended that administration of fluids commence as soon as possible to correct the water-electrolyte balance and replace urinary losses due to dehydration and post obstructive dieresis [1,3,4]. Inadequate replacement of fluids during the post obstructive period can delay resolution of these electrolytic, acid-base and uremic disturbances [4].…”

mentioning

confidence: 99%

“…It is suggested that the fluid accumulation in the HRG happened due to the association of several factors, such as increased hydrostatic pressure [5,7,10]. Hypoalbuminemia [3,6] and vasculitis [7], which could lead to pleural effusion and ascites. Hypoalbuminemia per se does not cause pulmonary interstitial edema [6].…”

mentioning

confidence: 99%

See 3 more Smart Citations

Fluid Therapy Rate in Postrenal Azotemia Stabilization in Cats

Cunha¹

2016

SOJVS

View full text Add to dashboard Cite

SOJ Veterinary Sciences Open Access Short CommunicationMetabolic acidosis may enhance hyperkalemic cardiotoxicity and venoconstriction, which, in turn, might promote clinical signs of fluid overload after intravenous administration of small fluid volumes [4]. There is not yet a consensus about the ideal rate of fluid therapy after relief of UO. Suggestions range between 10-90ml/kg/h for initial therapy in severe cases [1,4,7].The aim of the present paper was to alert veterinary clinicians about the influence of high rate of fluid therapy in the stabilization of cats with UO.This study was a pilot study from two other studies [8,9]. Fifteen neutered male adult mixed breed cats (weight range 3 to 5 kg) were housed in individual cages, fed dry commercial food and water was available ad libitum. The 15 cats were randomly allocated to receive a different rate of fluid therapy, with 5 cats in the High Rate Group (HRG) and 10 cats in the Low Rate Group (LRG). The initial rate for HRG was 40 mL/kg/h from 0 to 2 hours; this rate was reduced to 20 mL/kg/h from 2 to 12 hours, 15 mL/ kg/h from 12 to 24 hours, and 10 mL/kg/h from 24 to 48 hours. The initial rate for LRG was 20 mL/kg/h from 0 to 6 hours; this rate was reduced to 15 mL/kg/h from 6 to 12 hours, 10 mL/kg/h from 12 to 24 hours, and 5 mL/kg/h from 24 to 48 hours.All experimental procedures were reviewed and approved by the Federal University of Santa Maria Animal Care and Use Committee, number 031-2008. The animals were submitted to a urethral obstruction model [8,9] (parallel study) and submitted to the anesthetic for relieving of urethral obstruction when any 3 of 4 clinic pathologic criteria were met: venous pH < 7.2, BUN concentration > 200 mg/ dL, serum creatinine concentration > 4.5 mg/ dL, and serum potassium concentration > 6.5 mEq/ L.At predetermined time points, a blood sample was collected from the jugular vein to assess venous blood pH, pCO 2, pO 2 , bicarbonate concentration, BE, creatinine, BUN, sodium and potassium. The animals were weighed before urethral catheter placement and at 2, 4, 6, 8, 12 and 24 hours after UO removal. Venous blood gases, serum electrolyte analyses, creatinine and AbstractFluid therapy is the most important component involved in the stabilization of postrenal azotemia, however there is not yet a consensus about the ideal rate of fluid therapy after relief of urethral obstruction. Fifteen adult cats were divided in two groups: High Rate Group (HRG) and Low Rate Group (LRG). At predetermined time points was assessed venous blood pH, pCO 2, pO 2 , bicarbonate concentration, BE, creatinine, BUN, Na + , K + and urinary output. HRG had a lower glomerular filtration rate, characterized by a lower urinary output and a slower stabilization of BUN, creatinine, acidbase balance and potassium. The infusion of high rates of fluids in cats after a urethral obstruction must be undertaken with caution since it can lead to death due to the occurrence of pleural effusion and the absence of appropriate restoration of electrolyte balance and gl...

show abstract

Section: Cats Received Meloxicammentioning

confidence: 94%

mentioning

confidence: 99%

mentioning

confidence: 99%

mentioning

confidence: 99%

See 2 more Smart Citations

Fluid Therapy Rate in Postrenal Azotemia Stabilization in Cats

Cunha¹

2016

SOJVS

View full text Add to dashboard Cite

show abstract

“…While there are many conditions that can result in signs of feline lower urinary tract disease, the vast majority of cases are idiopathic (Gunn-Moore, 2003). This phenomenon contributes to the popularity of clinical studies (Gerber et al, 2005;Hostutler et al, 2005;Forrester and Roudebush, 2007) on feline urinary tract diseases. It is considered that the success of pathological evaluations and surgical approaches is closely related to the knowledge available on the normal anatomical features, arterial organisation and vascular variations of the lower urinary tract.…”

mentioning

confidence: 99%

Distribution of the arterial supply to the lower urinary tract in the domestic tom-cat (Felis catus)

Erdoğan¹

2011

Vet. Med. - Czech

View full text Add to dashboard Cite

This study was aimed at determining the arterial supply and gross vascular architecture of the urinary bladder in the male cat. For this purpose, the urinary bladders of 10 cats were evaluated. Organ vascularization was investigated using the latex injection technique. The feline urinary bladder was found to be supplied by the prostatic artery, which stemmed from the internal pudendal artery and the umbilical artery that originated from the internal iliac artery. The umbilical artery extended caudally to form the cranial vesical artery, which was later distributed into the corpus and apex of the urinary bladder. The feline prostatic artery divided into the artery of the deferent duct and a slim branch, which supplied the prostate gland. The artery of the deferent duct gave off a caudal vesical artery which gave off slim branches to the preprostatic urethra. On the surfaces of the urinary bladders examined, the cranial and caudal vesical arteries followed varying courses, which reflected individual variations. In all samples, the blood vessels generally divided into two or three branches on the surface of the urinary bladder, whilst in only one sample, the caudal vesical artery was observed to be of the ladder type. Moreover, the cranial and caudal vesical arteries anastomosed with each other on the surface of the urinary bladder. This study constitutes a model for comparison with other species and provides morphological contributions to anatomy training and surgical interventions since there is a lack of literature on species-specific vascular morphology in the field of veterinary urology in contrast to the abundance of studies on humans and rodents.

show abstract

Feline Idiopathic Cystitis

Westropp¹

2011

Nephrology and Urology of Small Animals

View full text Add to dashboard Cite

Recent concepts in feline lower urinary tract disease

Cited by 118 publications

References 35 publications

Fluid Therapy Rate in Postrenal Azotemia Stabilization in Cats

Fluid Therapy Rate in Postrenal Azotemia Stabilization in Cats

Distribution of the arterial supply to the lower urinary tract in the domestic tom-cat (Felis catus)

Feline Idiopathic Cystitis

Contact Info

Product

Resources

About