Recent development of high‐speed atomic force microscopy in molecular biology

Abstract

In the aspect of biomacromolecule imaging, high-speed atomic force microscopy (HS-AFM) has many wonderful characteristics, such as rapid imaging and real-time visualisation of the structure and dynamic behaviour of biological macromolecules, which is unparalleled by other technologies. In this review, state-of-the-art achievements on HS-AFM in molecular biology are summarised. Firstly, biomacromolecule characteristics determination and nanostructure recombination using HS-AFM are introduced, which confirm that HS-AFM is such a mature technology that realises high-speed imaging. Then, some improvements including the cantilever of HS-AFM, mechanical scanner, position sensor, and closed-loop control algorithm are reviewed to obtain higher resolution images. Finally, future development directions that could enhance the performance of HS-AFM are discussed.

Recent Progress in Gas Sensor Based on Nanomaterials

“…Silver nanoclusters are efficiently sensed by increasing the binding of silver phosphorene and weakening the silver-silver bond. Single Ag and Ag 1 phosphorene show that Ag atoms cannot only increase the adsorption energy but also increase the energy difference, which means that the phosphorene modified by single silver can improve the sensitivity of the four gas molecules [15]. NO 2 adsorption requires higher bias voltage than single silver-modified phosphorene.…”