2023
DOI: 10.1007/16833_2023_125
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Recent Development of Quinoline Derivatives as Anticancer Agents: 2015–2022

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Cited by 5 publications
(4 citation statements)
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“…In contrast, BDMC has been shown to induce G1/S arrest directly leading to mitotic block (Basile et al, 2009). Similarly, among the quaternary ammonium curcuminoids, compound 4 displayed enhanced tumour development inhibition as a solitary operator (Theppawong et al, 2018) and among the molecular hybrids of monocarbonyl curcumin and isatin, compounds 5-8 demonstrated cytotoxic effect against MiaPaca-2, PC-3, CAKI-I, HeLa, A549, HCT-116, THP-1, and COLO-205 human malignant growth cell lines (Kaur et al, 2016).…”
Section: P53/p21-mediated Apoptosismentioning
confidence: 99%
See 1 more Smart Citation
“…In contrast, BDMC has been shown to induce G1/S arrest directly leading to mitotic block (Basile et al, 2009). Similarly, among the quaternary ammonium curcuminoids, compound 4 displayed enhanced tumour development inhibition as a solitary operator (Theppawong et al, 2018) and among the molecular hybrids of monocarbonyl curcumin and isatin, compounds 5-8 demonstrated cytotoxic effect against MiaPaca-2, PC-3, CAKI-I, HeLa, A549, HCT-116, THP-1, and COLO-205 human malignant growth cell lines (Kaur et al, 2016).…”
Section: P53/p21-mediated Apoptosismentioning
confidence: 99%
“…Curcumin derivatives with furan moiety were reported to have a fantastic inhibitory impact on TrxR (thioredoxin reductase) irreversibly. Among many compounds screened, compound 79 is accounted for as most strong furan derivative (Kaur et al, 2016). The TrxR inhibition pathway is shown in Figure 8.…”
Section: Thioredoxin Reductase (Trxr) Inhibition Pathwaymentioning
confidence: 99%
“…The quinoline nucleus is ubiquitous in nature and plays a significant role in the development of novel heterocyclic compounds that have important pharmacological features, such as antitumoral activities [1,2]. Over time, studies of the biological activity of quinoline derivatives on diverse cancer cell lines have revealed a wide range of action mechanisms, paving the way for the development of more effective quinoline-derived drugs [3,4].…”
Section: Introductionmentioning
confidence: 99%
“…Moreover, the investigation into substituted quinoline compounds has garnered significant attention due to the pivotal role played by halogen atoms in conferring diverse biological activities [18], encompassing anticancer [19], anti-inflammatory [20], antioxidant [21] and antimicrobial properties [22]. The historical significance of penicillins as the inaugural efficacious antibiotics for microbial treatment is no coincidence, given their inclusion of a thiazole moiety [23].…”
mentioning
confidence: 99%