2024
DOI: 10.1063/5.0226060
|View full text |Cite
|
Sign up to set email alerts
|

Recent developments in microfluidic passive separation to enable purification of platelets for transfusion

Mai T. P. Dinh,
Mubasher Iqbal,
Kumar Abhishek
et al.

Abstract: Platelet transfusion is a lifesaving therapy intended to prevent and treat bleeding. However, in addition to platelets, a typical unit also contains a large volume of supernatant that accumulates multiple pro-inflammatory contaminants, including residual leukocytes, microaggregates, microparticles, antibodies, and cytokines. Infusion of this supernatant is responsible for virtually all adverse reactions to platelet transfusions. Conventional methods for removing residual leukocytes (leukoreduction) and reducin… Show more

Help me understand this report

Search citation statements

Order By: Relevance

Paper Sections

Select...

Citation Types

0
0
0

Publication Types

Select...

Relationship

0
0

Authors

Journals

citations
Cited by 0 publications
references
References 109 publications
0
0
0
Order By: Relevance

No citations

Set email alert for when this publication receives citations?