Recent improvements in the SHIELD-HIT code

Hansen, David C.; Lühr, Armin; Herrmann, Rochus; Sobolevsky, Nikolai; Bassler, Niels

doi:10.3109/09553002.2011.610863

Cited by 15 publications

(12 citation statements)

References 30 publications

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“…In order to simulate the ion transport in water the Monte Carlo (MC) transport code SHIELD-HIT (Dementyev & Sobolevsky 1999, Gudowska et al 2004) was employed in its latest version SHIELD-HIT10A (Hansen et al 2012b, Hansen et al 2012a. SHIELD-HIT10A is a MC code specialized to ion therapy.…”

Section: Shield-hit10amentioning

confidence: 99%

The impact of modeling nuclear fragmentation on delivered dose and radiobiology in ion therapy

et al. 2012

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Abstract.The importance of nuclear interactions for ion therapy arises from the influence of the particle spectrum on first, radiobiology and therefore also on treatment planning second, the accuracy of measuring dose and third, the delivered dose distribution. This study tries to determine the qualitative as well as quantitative influence of the modeling of inelastic nuclear interactions on ion therapy. Thereby, three key disciplines are investigated, namely, dose delivery, dose assessment, and radiobiology. In order to perform a quantitative analysis a relative comparison between six different descriptions of nuclear interactions is carried out for carbon ions. The particle transport is simulated with the Monte Carlo code SHIELD-HIT10A while dose planning and radiobiology are covered by the analytic treatment planning program for particles TRiP which determines the relative biological effectiveness (RBE) with the local effect model. The obtained results show that the physical dose distribution can in principle be significantly influenced by the modeling of fragmentation (about 10 % for a 20 % change in all inelastic nuclear cross sections for a target volume ranging from 15 cm to 25 cm). While the impact of nuclear fragmentation on stopping power ratios can be neglected the fluence correction factor may be influenced by the applied nuclear models. In contrast to the results for the physical dose, the variation of the RBE is only small (about 1 % for a 20 % change in all inelastic nuclear cross sections) suggesting a relatively weak dependence of radiobiology on the detailed composition of the particle energy spectrum of the mixed radiation field. Also, no significant change (about 0.2 mm) of the lateral penumbra of the RBE-weighted dose is observed.

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Section: Shield-hit10amentioning

confidence: 99%

The impact of modeling nuclear fragmentation on delivered dose and radiobiology in ion therapy

et al. 2012

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“…Previous to this work, the latest version of SHIELD-HIT was 08. In SHIELD-HIT10A several parameters regarding the nuclear reactions were changed along with several updates to the user interface and performance, which were partially discussed in (Hansen et al 2012).…”

Section: Introductionmentioning

confidence: 99%

Optimizing SHIELD-HIT for carbon ion treatment

et al. 2012

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The SHIELD-HIT Monte Carlo Transport code has been widely used in particle therapy, but has previously shown some discrepancies, when compared with experimental data. In this work, the inelastic nuclear cross sections of SHIELD-HIT are calibrated to experimental data for carbon ions. In addition, the models for nuclear fragmentation were adjusted to experiments, for the partial charge changing cross section of carbon ions in water. Comparison with fragmentation yield experiments for carbon and neon primaries were made for validation. For carbon primaries, excellent agreement between simulation and experiment was observed, with only minor discrepancies. For neon primaries, the agreement was also good, but larger discrepancies were observed, which require further investigation. In conclusion, the current version SHIELD-HIT10A is well suited for simulating problems arising in particle therapy for clinical ion beams.

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“…Eq. (12) can be extended to apply for compounds containing more than three elements, and the Pawlewicz correction can be used here as well. 2.…”

Section: Projectilementioning

confidence: 99%

“…SHIELD-HIT12A is a Monte Carlo particle transport code, which was specifically developed for transport of ions in biological tissues [11][12][13] for research purposes [14,15], and is based on earlier versions as presented in [16,17]. The aim of this work is to benchmark SHIELD-HIT12A to simulate the antiproton depth dose curve in water correctly.…”

Section: Introductionmentioning

confidence: 99%