Recent insights into therapeutic potential and nanostructured carrier systems of Centella asiatica: An evidence-based review

Bansal, Keshav; Bhati, Hemant; Vanshita,; Bajpai, Meenakshi

doi:10.1016/j.prmcm.2024.100403

Cited by 6 publications

(1 citation statement)

References 106 publications

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“…Centella is a genus comprising tropical and subtropical plants with around 59 species worldwide (Torbati et al, 2021). It holds significant importance in traditional medicine systems across Southeast Asian countries like India, Sri Lanka, China, Indonesia, and Malaysia, as well as in South Africa and Madagascar (Bansal et al, 2024;Hossain et al, 2018). Centella asiatica exhibits a wide range of pharmacological properties attributed to its bioactive constituents, including terpenic acids, flavonoids, and phenolic compounds (Kandasamy et al, 2023;Seevaratnam et al, 2012).…”

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confidence: 99%

Elevated salt stress level affected the productivity and chlorophyll content of Centella asiatica (L.)

Karmaker,

Robbani,

Islam

et al. 2024

Arch. Agric. Environ. Sci.

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Salinity disrupts plant nutrient uptake, metabolism, and increases susceptibility to biotic stresses. This reduces nutrient use efficiency, leading to stunted growth and decreased productivity. The aim of this study is to evaluate the growth and yield performance of Centella asiatica L. under varying levels of salt stress. The research was conducted at the Germplasm Centre, Department of Horticulture, Patuakhali Science and Technology University. A randomized complete block design with four replications was employed, wherein five salt concentrations i.e., 0 mM, 50 mM, 100 mM, 150 mM, and 200 mM were applied in four replications on 20 pots. Data on various growth and yield parameters were taken in four installments: 21, 42, 63, and 84 days after transplanting. Results showed that the highest values for various parameters were observed in the control group (2.34 mM base value), with notable figures including number of leaves (258.5), number of runners (126.75), petiole length (9.38 cm), chlorophyll content (41.62 SPAD value), fresh weight of leaves (23.92 g), dry weight of leaves (7.97 g), fresh weight of shoot (1.84 g), and dry weight of shoot (0.61 g) at 84 DAT. Conversely, fresh weight and dry weight of roots peaked at 150 mM salt concentration (1.95 g and 0.65 g, respectively). The investigations revealed that as salinity levels increased, a gradual decline in growth parameters was observed, indicating a significant reduction in the growth and yield of C. asiatica. These findings highlight the sensitivity of C. asiatica to salt stress and underscore the importance of salinity management for optimal growth and yield.

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Section: Introductionmentioning

confidence: 99%

Elevated salt stress level affected the productivity and chlorophyll content of Centella asiatica (L.)

Karmaker,

Robbani,

Islam

et al. 2024

Arch. Agric. Environ. Sci.

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Centella asiatica and its bioactive compounds: a comprehensive approach to managing hyperglycemia and associated disorders

Singh,

Singh

2024

Discov. Plants

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Centella asiatica (CA), (also known as Centella asiatica (L.) Urb. or Indian pennywort or Gotu Kola) is native to the tropical regions of Asia and Africa and has a rich history of use in treating a wide range of ailments, including neurological, dermatological, immunological, and metabolic disorders. This plant is rich in bioactive compounds, such as pentacyclic triterpenes (notably Asiaticoside, Asiatic Acid, Madecassoside, and Madecassic Acid), flavonoids, phytosterols, and phenolic acids, which contribute significantly to its therapeutic effectiveness. The medicinal applications of CA are vast, with its chemical constituents exhibiting notable therapeutic potential in areas such as antidiabetic, antimicrobial, anti-inflammatory, anticancer, neuroprotective, antioxidant, and wound healing activities. Numerous scientific investigations have validated these applications, confirming the efficacy of its bioactive components. In this critical review, we have conducted a comprehensive analysis of the existing literature to shed light on the pharmacological significance of CA, particularly concerning diabetes and related disorders.

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Emerging trends in pharmacological and therapeutic potential of glycyrrhizic acids: Traditional and nanotechnological approach

Jurel,

Bahadur,

Bajpai

2024

Pharmacological Research - Modern Chinese Medicine

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Recent insights into therapeutic potential and nanostructured carrier systems of Centella asiatica: An evidence-based review

Cited by 6 publications

References 106 publications

Elevated salt stress level affected the productivity and chlorophyll content of Centella asiatica (L.)

Elevated salt stress level affected the productivity and chlorophyll content of Centella asiatica (L.)

Centella asiatica and its bioactive compounds: a comprehensive approach to managing hyperglycemia and associated disorders

Emerging trends in pharmacological and therapeutic potential of glycyrrhizic acids: Traditional and nanotechnological approach

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