Recent progress in chemosensors based on pyrazole derivatives

Abstract

This review provides an overview on the recent (2016–2020) findings on chemosensors based on pyrazole derivatives. The discussion focuses on the design, physicochemical properties and practical applications of probes.

A simple colorimetric and ratiometric fluoride ion probe with large color change

“…Aer drying, the solvent was removed by vacuum distillation and puried by column chromatography with PE/EA (3/1, v/v) as an eluent to afford probe SHJ-1 (42 mg, yield: 89%). 1 (Fig. S7 †).…”

“…The sensing and recognition of anions have been considered as a hot topic due to the fundamental and crucial roles of anions in the environment and biological elds. [1][2][3][4][5][6][7][8][9][10] Among them, uoride is an essential trace element in the human body and widely exists in nature in the form of uorine ions. [11][12][13][14][15] Either deciency or excess of uoride in the human body would lead to dental caries, such as osteoporosis, uorosis and urolithiasis, and so on.…”

DBU-catalyzed Michael addition of bulky glycine imine to α,β-unsaturated isoxazoles and pyrazolamides

“…In these Michael reactions, acrylates and acrylamides, unsaturated nitriles and esters, linear and cyclic enones, vinyl phenyl sulfone, and aromatic nitroalkenes have been applied as Michael acceptors. On the 3 other hand, compounds with isoxazole and pyrazole ring exhibit a wide range of biological activities [40][41][42][43], such as anticancer, antimicrobial and anti-inflammatory effects ( Figure 1). By using glycine imines 1 and α,β-unsaturated isoxazoles 2 or pyrazolamides 3 as starting materials, many unnatural amino acids can be generated and severed as…”

Sulu Çözeltilerde Hg2+ Tespiti için Sinnamaldehit Türevi Bir Kolorimetrik Sensör

“…In recent years, several fluorescent sensors have been reported for the detection of Hg 2+ such as coumrain-based (Chen et al, 2019;Cao et al, 2019), rhodamine-based (Aydin et al, 2014;Hong et al, 2019), perylene-based (Chen et al, 2020), and pyrozole-based (Tigreros and Portilla, 2020) sensors. Most recently, colorimetric sensors have been gaining interest owing to their applicability by common people (Upadhyay et al, 2019).…”