Recent progress in development and applications of second near‐infrared (NIR-II) nanoprobes

Shinn, Jongyoon; Lee, Sun Young; Lee, Hyon Kyong; Ahn, Jaeeun; Lee, Seon Ah; Lee, Seonju; Yong-Hyun, Lee

doi:10.1007/s12272-021-01313-x

Cited by 24 publications

(14 citation statements)

References 101 publications

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“…Meanwhile, hydrogels maintain a sustained release of Cu 2+ and create a moist microenvironment, helping skin wound healing 179 . To compensate for the lack of penetration depth of NIR‐I, PTAs that absorb NIR‐II have been extensively studied 63,180,181 . Xu et al designed NIR‐II‐activated hollow nanocarbons termed HPP.…”

Section: Biomedical Applications Of Temperature‐dependent Pttmentioning

confidence: 99%

Biomedical applications and prospects of temperature‐orchestrated photothermal therapy

Zhang

et al. 2022

MedComm – Biomaterials and Applications

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Photothermal therapy (PTT) has been regarded as a promising strategy considering its advantages of high inherent specificity and a lower invasive burden. Since the photothermal killing of cells/bacteria showed different patterns of death depending on the varying temperature in PTT, the temperature change of PTT is vital to cell/tissue response in scientific research and clinical application. On one hand, mild PTT has received substantial attention in the treatment of cancer and soft/hard tissue repair. On the other hand, the high temperature induced by PTT is capable of antibacterial capacity, which is better than conventional antibiotic therapy with drug resistance. Herein, we summarize the recent developments in the application of temperature-dependent photothermal biomaterials, mainly covering the temperature ranges of 40-42°C, 43-50°C, and over 50°C. We highlight the biological mechanism of PTT and the latest progress in the treatment of different diseases. Finally, we conclude by discussing the challenges and perspectives of biomaterials in addressing temperatureorchestrated PTT. Given a deep understanding of the interaction between temperature and biology, rationally designed biomaterials with sophisticated photothermal responsiveness will benefit the outcomes of personalized PTT toward various diseases.

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Section: Biomedical Applications Of Temperature‐dependent Pttmentioning

confidence: 99%

Biomedical applications and prospects of temperature‐orchestrated photothermal therapy

Zhang

et al. 2022

MedComm – Biomaterials and Applications

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“…Therefore, the multi-channel imaging techniques and multi-response probes should be developed for NIR-II in vivo quantitative analysis. Multi-response NIR-II probes can respond to different analytes and have differentiable signals for various analytes, and the real-time multi-channel NIR-II imaging techniques can simultaneously record multiple events ( Fan et al, 2018 ; Cao J. et al, 2019 ; Wang T. et al, 2021 ; Shinn et al, 2021 ), providing more in vivo quantitative properties for understanding the physiological and pathological processes of living bodies.…”

Section: Perspectives and Challengesmentioning

confidence: 99%

Near-Infrared-II Bioimaging for in Vivo Quantitative Analysis

et al. 2021

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Near-Infrared-II (NIR-II) bioimaging is a newly emerging visualization modality in real-time investigations of biological processes research. Owning to advances in reducing photon scattering and low tissue autofluorescence levels in NIR-II region (1,000–1700 nm), NIR-II bioimaging affords high resolution with increasing tissue penetration depth, and it shows greater application potential for in vivo detection to obtain more detailed qualitative and quantitative parameters. Herein, this review summarizes recent progresses made on NIR-II bioimaging for quantitative analysis. These emergences of various NIR-II fluorescence, photoacoustic (PA), luminescence lifetime imaging probes and their quantitative analysis applications are comprehensively discussed, and perspectives on potential challenges facing in this direction are also raised.

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“…33,34 Especially, the second NIR window (NIR-II, 1000− 1350 nm) presents a lower background signal, better light penetration, and higher safety limit than the NIR-I window (650−950 nm). 35,36 PAI of targeted areas located deep within biological tissues like the heart cannot be realized by other superficial methods. 37 The particular optical and electronic properties of the Au nanomaterials have been proven to endow a wide range of bioapplications.…”

Section: Introductionmentioning

confidence: 99%

“…In addition, the real-time noninvasive tracer could better evaluate the efficiency of the targeted drug delivery to the treatment site . However, tracing drug delivery to the heart has always been a problem, and photoacoustic imaging (PAI) techniques with the advantages of high sensitivity, strong tissue penetration, and high spatial resolution were widely studied. , Especially, the second NIR window (NIR-II, 1000–1350 nm) presents a lower background signal, better light penetration, and higher safety limit than the NIR-I window (650–950 nm). , PAI of targeted areas located deep within biological tissues like the heart cannot be realized by other superficial methods . The particular optical and electronic properties of the Au nanomaterials have been proven to endow a wide range of bioapplications .…”

Section: Introductionmentioning

confidence: 99%

Light-Activated Gold–Selenium Core–Shell Nanocomposites with NIR-II Photoacoustic Imaging Performances for Heart-Targeted Repair

Sun

Zhang

et al. 2022

ACS Nano

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Mitochondrial dysfunction and oxidative damage represent important pathological mechanisms of myocardial ischemia-reperfusion injury (MI/RI). Searching for potential antioxidant agents to attenuate MI/RI is of great significance in clinic. Herein, gold–selenium core–shell nanostructures (AS-I/S NCs) with good near-infrared (NIR)-II photoacoustic imaging were designed for MI/RI treatment. The AS-I/S NCs after ischemic myocardium-targeted peptide (IMTP) and mitochondrial-targeted antioxidant peptide SS31 modification achieved cardiomyocytes-targeted cellular uptake and enhanced antioxidant ability and significantly inhibited oxygen-glucose deprivation-recovery (OGD/R)-induced cardiotoxicity of H9c2 cells by inhibiting the depletion of mitochondrial membrane potential (MMP) and restoring ATP synthase activity. Furthermore, the AS-I/S NCs after SS31 modification achieved mitochondria-targeted inhibition of reactive oxygen species (ROS) and subsequently attenuated oxidative damage in OGD/R-treated H9c2 cells by inhibition of apoptosis and oxidative damage, regulation of MAPKs and PI3K/AKT pathways. The in vivo AS-I/S NCs administration dramatically improved myocardial functions and angiogenesis and inhibited myocardial fibrosis through inhibiting myocardial apoptosis and oxidative damage in MI/RI of rats. Importantly, the AS-I/S NCs showed good safety and biocompatibility in vivo. Therefore, our findings validated the rational design that mitochondria-targeted selenium–gold nanocomposites could attenuate MI/RI of rats by inhibiting ROS-mediated oxidative damage and regulating MAPKs and PI3K/AKT pathways, which could be a potential therapy for the MI/RI treatment.

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Recent progress in development and applications of second near‐infrared (NIR-II) nanoprobes

Cited by 24 publications

References 101 publications

Biomedical applications and prospects of temperature‐orchestrated photothermal therapy

Biomedical applications and prospects of temperature‐orchestrated photothermal therapy

Near-Infrared-II Bioimaging for in Vivo Quantitative Analysis

Light-Activated Gold–Selenium Core–Shell Nanocomposites with NIR-II Photoacoustic Imaging Performances for Heart-Targeted Repair

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