Recent progress in the development of fluorescent probes for hydrazine

Abstract

Hydrazine (N H ) is an important and commonly used chemical reagent for the preparation of textile dyes, pharmaceuticals, pesticides and so on. Despite its widespread industrial applications, hydrazine is highly toxic and exposure to this chemical can cause many symptoms and severe damage to the liver, kidneys, and central nervous system. As a consequence, many efforts have been devoted to the development of fluorescent probes for the selective sensing and/or imaging of N H . Although great efforts have been devoted in this area, the large number of important recent studies have not yet been systematically discussed in a review format so far. In this review, we have summarized the recently reported fluorescent N H probes, which are classified into several categories on the basis of the recognition moieties. Moreover, the sensing mechanism and probes designing strategy are also comprehensively discussed on aspects of the unique chemical characteristics of N H and the structures and spectral properties of fluorophores.

Hydrazine-Selective Fluorescent Turn-On Probe Based on Ortho-Methoxy-Methyl-Ether (o-MOM) Assisted Retro-aza-Henry Type Reaction

“…We expected the negligible fluorescence of HyP-2 dipolar backbone due to the effect of polarity on charge redistribution in molecule within aqueous media [28,29,30]. The addition of hydrazine can induce the cleavage of the dicyanovinyl group [16] and cascade hydrazone-formation via retro-aza-Henry type reaction, and it could be accelerated by o -MOM moiety. Using this process, the fluorescence of HyP-2 was recovered as a turn-on manner due to the elimination of non-radiative decay pathway.…”

“…Thus far, many fluorescent probes that can sense hydrazine have been reported [16]. The working mechanisms of known probes are mostly based on (i) hydrazine-triggered sensing moiety cleavage, (ii) hydrazine-addition induced sensing moiety transformation.…”

Articulated Structures of D-A Type Dipolar Dye with AIEgen: Synthesis, Photophysical Properties, and Applications

“…In addition, the environment-dependent emission changes were not observed in DI H 2 O. In other words, the emission intensities of the DA-AIE series are independent of the solvent viscosity ( Figure S3), metal ions, and hydrazine (N 2 H 4 ), which could form hydrazone with the aldehyde functional group in DA moieties ( Figure S4) [32].…”

Impact of Weak Organic Acids on Precipitation of Poly(acrylic acid) Stabilized Silver Nanoparticles; an Electrochemical Approach

“…Although hydrazine is an explosive and hazardous molecule, [32] it is also a low-cost, highly available chemical and a fast reduction agent, which renders small nanoparticles with unique optoelectronical and physicochemical properties. In recent years there have been a lot of published scientific articles regarding green nanosilver preparation, [33][34][35] but our synthetic route is a strictly controlled process which ensures that all of the reducing agent transfers into elementary nitrogen.…”