Recent Progress of Chiral Iminophosphorane Catalysis

Abstract

As organocatalysts, organic base catalysts play an important role in the quest for optically pure compounds. Chiral iminophosphoranes, being organosuperbases, are very stable under air and moisture conditions, thereby providing an attractive platform for the design of various asymmetric organocatalysts. The recent achievements concerning chiral iminophosphoranes in the development of both organocatalysis and their applications in asymmetric synthesis are summarized and discussed. Keywords chiral iminophosphorane; asymmetric catalysis; research progress; organocatalysis