Recent progress on cell-based biosensors for analysis of food safety and quality control

Ye, Yongli; Guo, Hongyan; Sun, Xiulan

doi:10.1016/j.bios.2018.10.039

Cited by 108 publications

(43 citation statements)

References 131 publications

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“…The selective detection of pathogens in food and water remains a global healthcare challenge. Several comprehensive reviews have been written on biosensors for food and water safety (Baeumner, 2003;Bozal-Palabiyik et al 2018;Leonard et al 2003;Ye et al, 2019). Here, we describe the most common foodborne and waterborne pathogens.…”

Section: Food and Water Safety Applicationsmentioning

confidence: 99%

“…Alternatively, those for water safety applications in under-developed regions may require biosensor designs and measurement formats that facilitate field use, such as sample preparation-free protocols. Pathogens can also enter food and water through processing, packaging, distribution, and storage processes (e.g., via workers and pests) (Beuchat et al 2013;Mehrotra, 2016;Ye et al, 2019). As a result, biosensors for food and water safety applications should facilitate pathogen detection at various stages of the processing operation.…”

Section: Food and Water Safety Applicationsmentioning

confidence: 99%

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Electrochemical biosensors for pathogen detection

Cesewski

Johnson

2020

Biosensors and Bioelectronics

635

358

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A B S T R A C TRecent advances in electrochemical biosensors for pathogen detection are reviewed. Electrochemical biosensors for pathogen detection are broadly reviewed in terms of transduction elements, biorecognition elements, electrochemical techniques, and biosensor performance. Transduction elements are discussed in terms of electrode material and form factor. Biorecognition elements for pathogen detection, including antibodies, aptamers, and imprinted polymers, are discussed in terms of availability, production, and immobilization approach. Emerging areas of electrochemical biosensor design are reviewed, including electrode modification and transducer integration. Measurement formats for pathogen detection are classified in terms of sample preparation and secondary binding steps. Applications of electrochemical biosensors for the detection of pathogens in food and water safety, medical diagnostics, environmental monitoring, and bio-threat applications are highlighted. Future directions and challenges of electrochemical biosensors for pathogen detection are discussed, including wearable and conformal biosensors, detection of plant pathogens, multiplexed detection, reusable biosensors for process monitoring applications, and low-cost, disposable biosensors.

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Section: Food and Water Safety Applicationsmentioning

confidence: 99%

Section: Food and Water Safety Applicationsmentioning

confidence: 99%

Electrochemical biosensors for pathogen detection

Cesewski

Johnson

2020

Biosensors and Bioelectronics

635

358

View full text Add to dashboard Cite

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“…Other recent approaches reported for the detection of allergens at the protein level include new peptidomics and proteomics methods, flow cytometry and immunochromatography [1], surface plasmon resonance (SPR) [17] and cell-based biosensors [18].…”

Section: Conventional Methods To Determine Food Allergens and Adultermentioning

confidence: 99%

Cutting-Edge Advances in Electrochemical Affinity Biosensing at Different Molecular Level of Emerging Food Allergens and Adulterants

et al. 2020

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The presence of allergens and adulterants in food, which represents a real threat to sensitized people and a loss of consumer confidence, is one of the main current problems facing society. The detection of allergens and adulterants in food, mainly at the genetic level (characteristic fragments of genes that encode their expression) or at functional level (protein biomarkers) is a complex task due to the natural interference of the matrix and the low concentration at which they are present. Methods for the analysis of allergens are mainly divided into immunological and deoxyribonucleic acid (DNA)-based assays. In recent years, electrochemical affinity biosensors, including immunosensors and biosensors based on synthetic sequences of DNA or ribonucleic acid (RNA), linear, aptameric, peptide or switch-based probes, are gaining special importance in this field because they have proved to be competitive with the methods commonly used in terms of simplicity, test time and applicability in different environments. These unique features make them highly promising analytical tools for routine determination of allergens and food adulterations at the point of care. This review article discusses the most significant trends and developments in electrochemical affinity biosensing in this field over the past two years as well as the challenges and future prospects for this technology.

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“…The whole cells that are used as sensing elements can offer in real-time valuable information which is related to their physiological status and microenvironment, and depending on their affinity could be used for the detection of disease biomarkers, pollutants, and micronutrients. The detection of foodborne pathogens, quantification of toxins, analysis of allergens, contamination of food with heavy metals and/or antibiotics, represents another side of the applications of this type of biosensors in food safety and quality control (Ye et al 2018).…”

Section: Generalities Electrochemical Approachmentioning

confidence: 99%