2023
DOI: 10.3390/molecules28176186
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Recent Progresses in the Catalytic Stereoselective Dearomatization of Pyridines

Lucrezia Margherita Comparini,
Mauro Pineschi

Abstract: 1,2- and 1,4-dihydropyridines and N-substituted 2-pyridones are very important structural motifs due to their synthetic versatility and vast presence in a variety of alkaloids and bioactive molecules. In this article, we gather and summarize the catalytic and stereoselective synthesis of partially hydrogenated pyridines and pyridones via the dearomative reactions of pyridine derivatives up to mid-2023. The material is fundamentally organized according to the type of reactivity (electrophilic/nucleophilic) of t… Show more

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Cited by 8 publications
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References 78 publications
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