Recent reports on electrochemical determination of selected antibiotics in pharmaceutical formulations: A mini review

Bitew, Zelalem; Amare, Meareg

doi:10.1016/j.elecom.2020.106863

Cited by 34 publications

(16 citation statements)

References 56 publications

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“…The most common antibiotics detected in environmental water are classified into the following categories: beta‐lactams (β‐lactams), quinolones (Qs), sulfonamides antibiotics (SAs), macrolides (MAs), tetracyclines (TCs), aminoglycosides (AMGs), and phenicols [3]. Antibiotics in environmental water pose a potential risk to ecosystems because of their persistent toxicity to environmental microorganisms through a complex vicious cycle of transformation and bioaccumulation [4]. More importantly, antibiotic residues in environmental water have the potential to produce antibiotic‐resistant bacteria and promote antibiotic resistance genes, which pose serious public health risks that are sometimes impossible to cure [5,6].…”

Section: Introductionmentioning

confidence: 99%

Single‐drop microextraction technique for the determination of antibiotics in environmental water

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2022

J of Separation Science

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Growing concerns related to antibiotic residues in environmental water have encouraged the development of rapid, sensitive, and accurate analytical methods. Single‐drop microextraction has been recognized as an efficient approach for the isolation and preconcentration of several analytes from a complex sample matrix. Thus, single‐drop microextraction techniques are cost‐effective and less harmful to the environment, subscribing to green analytical chemistry principles. Herein, an overview and the current advances in single‐drop microextraction for the determination of antibiotics in environmental water are presented were included. In particular, two main approaches used to perform single‐drop microextraction (direct immersion‐single‐drop microextraction and headspace‐single‐drop microextraction) are reviewed. Furthermore, the impressive analytical features and future perspectives of single‐drop microextraction are discussed in this review.

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Section: Introductionmentioning

confidence: 99%

Single‐drop microextraction technique for the determination of antibiotics in environmental water

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2022

J of Separation Science

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“…In the literature, the use of different techniques was reported for separation or quantitative MNZ detection in environmental and biological samples, human plasma, drugs, and food products. They include high-performance liquid chromatography [ 11 ], liquid chromatography-tandem mass spectrometric method (LC-MS/MS) [ 12 ], chemiluminescence [ 13 ] fluorescence [ 14 , 15 ], near-infrared spectrophotometry (NIRS) [ 16 ], spectrophotometry [ 17 , 18 , 19 ], voltammetry with chemically modified electrodes [ 20 , 21 , 22 , 23 , 24 , 25 , 26 , 27 , 28 , 29 ].…”

Section: Introductionmentioning

confidence: 99%

Study on Metronidazole Acid-Base Behavior and Speciation with Ca2+ for Potential Applications in Natural Waters

et al. 2022

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Metronidazole (MNZ) is an antibiotic widely used for the treatment of various infectious diseases and as an effective pesticide agent for the cultivation of chickens and fish. Its high resistance to purification processes and biological activity has led to the classification of MNZ as an emerging contaminant. A speciation study, aimed to define the acid-base properties of MNZ and its interaction with Ca2+, commonly present in natural waters, is reported. The protonation constants of MNZ, as well as the formation constant value of Ca2+-MNZ species, were obtained by potentiometric titrations in an aqueous solution, using NaCl as background salt at different ionic strengths (0.15, 0.5, 1 mol L−1) and temperature (15, 25 and 37 °C) conditions. The acid-base behavior and the complexation with Ca2+ were also investigated by 1H NMR and UV-Vis titrations, with results in very good agreement with the potentiometric ones. The dependence of the formation constants on the ionic strength and temperature was also determined. The sequestering ability of MNZ towards Ca2+ was defined by the empirical parameter pL0.5 at different pH and temperature values. The speciation of MNZ simulating sea water conditions was calculated.

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“…In medicine, EC based methods are routinely used for quick and inexpensive detection of various biomarkers, pathogens and metabolites [9] . In industry, product quality control is a prime area where EC is utilized, e. g., for drug analysis [10] . The EC methods are used not only in hi‐tech pharma laboratories, but also in food quality control laboratories where dairy products are inspected [11] .…”

Section: Introductionmentioning

confidence: 99%

“…The extent of the applications of EC methods is very impressive indeed, and it is difficult to mention them all. Comprehensive discussions about the enormous success of EC applications can be found in many thorough review articles [6,9–11] …”

Section: Introductionmentioning

confidence: 99%

Recent Progress in Liquid State Electrochemistry Coupled with NMR Spectroscopy

et al. 2021

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Analytical methods of electrochemistry (EC) are relatively inexpensive, and widely used in science, industry, and medicine. Although EC is distinguished by its high sensitivity, it does not provide direct and detailed data about the bond connectivity or dynamics of the molecular system. Conversely, Magnetic Resonance (MR) gives comprehensive insights into the structure and dynamics of molecules but suffers from low sensitivity. The strengths and shortcomings of EC and NMR are thus complementary. The combination of these orthogonal techniques into EC‐NMR creates a powerful tool that should be able to provide analytical data barely available for EC or NMR alone. This review presents recent developments in the field of EC‐NMR – we describe experimental designs with electrodes made of metal wires, thin films, and nonmetallic materials, as well as performance improvements achieved by the implementation of micro‐NMR, hyperpolarization, new pulse sequences, and 3D printing. We also review the application of EC‐NMR in catalysis for sustainable energy conversion.

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Recent reports on electrochemical determination of selected antibiotics in pharmaceutical formulations: A mini review

Cited by 34 publications

References 56 publications

Single‐drop microextraction technique for the determination of antibiotics in environmental water

Single‐drop microextraction technique for the determination of antibiotics in environmental water

Study on Metronidazole Acid-Base Behavior and Speciation with Ca2+ for Potential Applications in Natural Waters

Recent Progress in Liquid State Electrochemistry Coupled with NMR Spectroscopy

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