Recent trends in anti-obesity and anti-inflammatory studies in modern health care

Na, Eun-Ju; Kim, Dojin; Kim, Jong-Hyuck; Kim, Gyu-Ri

doi:10.3233/thc-191736

Cited by 8 publications

(6 citation statements)

References 12 publications

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“…One of the researches recruited for this discussion assessed the effectiveness of the compound in the treatment of burns in mice (31) . Despite this, there is evidence about the anti-inflammatory action of two of its main active components, myrrh (32)(33)(34) , and sanguisorba (35)(36)(37) .…”

Section: Article Identificationmentioning

confidence: 99%

Effectiveness of skin protectors and calendula officinalis for prevention and treatment of radiodermatitis: an integrative review

et al. 2020

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Objective: to analyze the effectiveness of skin protectors and Calendula officinalis for prevention and treatment of radiodermatitis. Method: an integrative review conducted at CINAHL, Cochrane Library, Embase, MEDLINE/PubMed, IBECS, LILACS, and Web of Science. The final sample consisted of five studies, four clinical studies and one preclinical. Critical appreciation and narrative synthesis of the findings were carried out. Results: the Cavilon™ skin protector was more effective than Sorbolene (cream with 10% glycerin) and less effective than Mometasone Furoate cream. Calendula officinalis was more effective than Trolamine and essential fatty acids and less effective than Ching Wan Hung® for prevention and treatment of radiodermatitis. Conclusion: data confirm the potential of Calendula officinalis for prevention and treatment of radiodermatitis and point to promising results regarding skin protector use; however, there is a need for further testing as to the effectiveness of such products.

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Section: Article Identificationmentioning

confidence: 99%

Effectiveness of skin protectors and calendula officinalis for prevention and treatment of radiodermatitis: an integrative review

et al. 2020

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“…Some metabolites showed different patterns for each fermented group. Unlike the GF group, the AF group showed a decrease in casticin (37) and an increase in pyroglutamyl-valine (1), pyroglutamyl-leucine (2), lactotyl-tryptophan (3), hydroxyglutaric acid (5), dihydrocaffeic acid (13), scopoletin (17), phloretic acid (19), 3-caffeoylquinic acid (21), 3,4-dicaffeoylquinic acid (23), 3-feruloyl-4-caffeoylquinic acid (24), hydroxybenzoic acid (30), syringic aldehyde (33), 4-ethylcatechol (32), 4-vinylcatechol (31), shikimic acid (38), and two non-identified metabolites (40,42) (Figure 2C). Relatedly, 9-DiHODE (8), 9,10-DiHOME (9), and N.I 2 (41) increased only in SF (Figure 2D).…”

Section: Relative Metabolite Abundance In Annual Wormwood and Glasswo...mentioning

confidence: 99%

Effects of Fermented Artemisia annua L. and Salicornia herbacea L. on Inhibition of Obesity In Vitro and In Mice

Kim

et al. 2023

Nutrients

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Plant extracts including secondary metabolites have anti-inflammatory and anti-obesity activities. This study was conducted to investigate the anti-obesity properties of fermented Artemisia annua (AW) and Salicornia herbacea (GW) in vitro and in mice. The metabolite profiling of AW and GW extracts was performed using UHPLC−LTQ−Orbitrap–MS/MS, and gene expression was analyzed using real-time PCR for adipocyte difference factors. The anti-obesity effects in mice were measured using serum AST, ALT, glucose, TG, and cholesterol levels. Metabolites of the plant extracts after fermentation showed distinct differences with increasing anti-obesity active substances. The efficacy of inhibitory differentiation adipogenesis of 3T3-L1 adipocytes was better for GW than AW in a concentration-dependent manner. RT-PCR showed that the GW extract significantly reduced the expression of genes involved in adipocyte differentiation and fat accumulation (C/EBPα, PPARγ, and Fas). In C57BL/6 mice fed the HFD, the group supplemented with AW and GW showed reduced liver weight, NAS value, and fatty liver by suppressing liver fat accumulation. The GW group significantly reduced ALT, blood glucose, TG, total cholesterol, and LDL-cholesterol. This study displayed significant metabolite changes through biotransformation in vitro and the increasing anti-obesity effects of GW and AW in mice. GW may be applicable as functional additives for the prevention and treatment of obesity.

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“…In the Armenian region, the aerial part of S. officinalis has been in use as a traditional medicine for treating different diseases (Ginovyan et al, 2020). Studies reported in recent years have provided scientific evidence that the components present in the different parts of S. officinalis plant are indeed different (Na et al, 2019). It is reported that the aerial parts of S. officinalis contain higher amount of polyphenols compared to its roots (Bunse et al, 2020).…”

Section: Traditional Uses Of Genus Sanguisorba Plantsmentioning

confidence: 99%

A Comprehensive Review of Genus Sanguisorba: Traditional Uses, Chemical Constituents and Medical Applications

Zhou

Chen

et al. 2021

Front. Pharmacol.

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Genus Sanguisorba (family: Rosaceae) comprises nearly 148 species, distributed widely across the temperate and subtropical regions of the Northern Hemisphere. Sanguisorba officinalis L. (S. officinalis) has been used as a hemostatic and scald treating medicine in China for a long time. Numerous studies have demonstrated that plant extracts or monomers from S. officinalis exhibit several pharmacological effects, such as anti-cancer, anti-virus, anti-inflammation, anti-bacteria, neuroprotective and hepatoprotective effects. The other species of genus Sanguisorba are also being studied by researchers worldwide. Sanguisorba minor Scop. (S. minor), as an edible wild plant, is a common ingredient of the Mediterranean diet, and its young shoots and leaves are often mixed with traditional vegetables and consumed as salad. Reports on genus Sanguisorba available in the current literature were collected from Google Scholar, Web of Science, Springer, and PubMed. The Plant List (http://www.theplantlist.org./tpl1.1/search?q=Sanguisorba), International Plant Name Index (https://www.ipni.org/?q=Sanguisorba) and Kew Botanical Garden (http://powo.science.kew.org/) were used for obtaining the scientific names and information on the subspecies and cultivars. In recent years, several in vivo and in vitro experiments have been conducted to reveal the active components and effective monomers of S. officinalis and S. minor. To date, more than 270 compounds have been isolated and identified so far from the species belonging to genus Sanguisorba. Numerous reports on the chemical constituents, pharmacologic effects, and toxicity of genus Sanguisorba are available in the literature. This review provides a comprehensive understanding of the current traditional applications of plants, which are supported by a large number of scientific experiments. Owing to these promising properties, this species is used in the treatment of various diseases, including influenza virus infection, inflammation, Alzheimer’s disease, type 2 diabetes and leukopenia caused by bone marrow suppression. Moreover, the rich contents and biological effects of S. officinalis and S. minor facilitate these applications in dietary supplements and cosmetics. Therefore, the purpose of this review is to summarize the recent advances in the traditional uses, chemical constituents, pharmacological effects and clinical applications of genus Sanguisorba. The present comprehensive review may provide new insights for the future research on genus Sanguisorba.

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Recent trends in anti-obesity and anti-inflammatory studies in modern health care

Cited by 8 publications

References 12 publications

Effectiveness of skin protectors and calendula officinalis for prevention and treatment of radiodermatitis: an integrative review

Effectiveness of skin protectors and calendula officinalis for prevention and treatment of radiodermatitis: an integrative review

Effects of Fermented Artemisia annua L. and Salicornia herbacea L. on Inhibition of Obesity In Vitro and In Mice

A Comprehensive Review of Genus Sanguisorba: Traditional Uses, Chemical Constituents and Medical Applications

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