Recent trends in polymeric composites and blends for three-dimensional printing and bioprinting

Yeleswarapu, Sriya; Vijayasankar, K N; Chameettachal, Shibu; Pati, Falguni

doi:10.1016/b978-0-323-88524-9.00004-8

Cited by 1 publication

(3 citation statements)

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“…38 In this regard, polymer blending and filler compounding of the filament material have been described to lower the melting temperature, broaden the thermal stability range, or tailor the rheological properties, leading to a higher resolution of 3D-printed scaffolds. 39,40 Therefore, in the present study, we aimed to advance and support the use of a solvent-free, low-cost, and straightforward AM technology, such as FFF, for the fabrication of 3D-printed scaffolds. We wanted these scaffolds to be able to support tissue regeneration processes and to be bioresorbable so that they could be naturally reabsorbed by the human body at the end of the healing process.…”

Section: Introductionmentioning

confidence: 99%

“…To be processed in FFF, the polymer should have sufficient thermal stability and an adequate rheological behavior to avoid a drop in molecular weight due to thermal degradation during the printing process . In this regard, polymer blending and filler compounding of the filament material have been described to lower the melting temperature, broaden the thermal stability range, or tailor the rheological properties, leading to a higher resolution of 3D-printed scaffolds. , …”

Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

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3D-Printed Poly(3-hydroxybutyrate-co-3-hydroxyhexanoate)-Cellulose-Based Scaffolds for Biomedical Applications

Giubilini,

Messori,

Bondioli

et al. 2023

Biomacromolecules

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While biomaterials have become indispensable for a wide range of tissue repair strategies, second removal procedures oftentimes needed in the case of non-bio-based and nonbioresorbable scaffolds are associated with significant drawbacks not only for the patient, including the risk of infection, impaired healing, or tissue damage, but also for the healthcare system in terms of cost and resources. New biopolymers are increasingly being investigated in the field of tissue regeneration, but their widespread use is still hampered by limitations regarding mechanical, biological, and functional performance when compared to traditional materials. Therefore, a common strategy to tune and broaden the final properties of biopolymers is through the effect of different reinforcing agents. This research work focused on the fabrication and characterization of a bio-based and bioresorbable composite material obtained by compounding a poly(3hydroxybutyrate-co-3-hydroxyhexanoate) (PHBH) matrix with acetylated cellulose nanocrystals (CNCs). The developed biocomposite was further processed to obtain three-dimensional scaffolds by additive manufacturing (AM). The 3D printability of the PHBH−CNC biocomposites was demonstrated by realizing different scaffold geometries, and the results of in vitro cell viability studies provided a clear indication of the cytocompatibility of the biocomposites. Moreover, the CNC content proved to be an important parameter in tuning the different functional properties of the scaffolds. It was demonstrated that the water affinity, surface roughness, and in vitro degradability rate of biocomposites increase with increasing CNC content. Therefore, this tailoring effect of CNC can expand the potential field of use of the PHBH biopolymer, making it an attractive candidate for a variety of tissue engineering applications.

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Section: Introductionmentioning

confidence: 99%