“…Nevertheless, many reviews of international epidemiological studies suggested that the prevalence of severe MR (SMR) is approximately 3 to 4 per 1000 in children [Starza-Smith, 1989;Roeleveld et al, 1997] and in adults [Reschly, 1992] in both developed and developing countries [Kiely, 1987]. Figures 1 and 2, showing the prevalence of SMR and MMR, have been adapted from Roeleveld et al [1997] and modified by the inclusion of recent studies F, G, S, C and L [Fernell et al, 1996;Fernell et al, 1998;Stromme and Valvatne, 1998;Gissler et al, 1999;Cans et al, 1999;Leonard et al, 2002a].…”