In order to promote the development of environmental protection, and the usage rate of green energy utilization, a progressive, innovative laser process method employing helium assisted is proposed, which optimizes the joint cutting process under the same energy consumption. This method provides a new idea for the wood process industry. The uniqueness of this paper establishes a mathematical model to address the diffusion of helium injection and the heat transfer of the laser beam on the processed surface. From the results, it can be exhibited that the oxygen concentration reduces when the helium is injected on the processed surface. The helium could destroy the combustion-supporting conditions and decrease the combustion zone of the processed joint cutting. Thus, the carbonized area of the processed surface is reduced, which could effectively enhance the processing quality of joint cutting. Notably, the helium with injection speed forms a sweeping effect on the processed surface, which could remove parts of the carbonized particles and residues on the processed surface, as well as improve the processing quality. Comparing the traditional laser process and helium-assisted laser process, the gas-assisted laser process owns higher process quality than that of traditional laser processing and cutting. In detail, it features the advantages of smaller joint cutting width, lower surface roughness and smoother surface. Eventually, a mathematical model based on the response surface method with the evaluation criteria of the kerf width, kerf depth, and surface roughness is established to analyze the interaction of laser power, cutting speed and inert gas pressure on the response factors. Comparing the error between the predicted and experimental measurement value, and the optimized process parameters could be acquired. In this paper, the helium-assisted laser process method proposed is meaningful and encouraging, which not only obtains better processing quality, but also provides a guide for developing green industry.