Récidive d’un angiomyxome périnéal agressif : une chirurgie d’exérèse incomplète est-elle utile ?

Khelifi, Slim; Ali, A. Ben; Tagougui, W.; Jaoua, Hazem; Chammakhi, Chiraz; Chadly, Ali; Bouhafa, Ahmed; Maamar, Anis Ben; Cherif, Abderraouf

doi:10.1016/j.jchir.2009.08.017

Cited by 4 publications

(2 citation statements)

References 18 publications

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“…Because of the nature of AAM invasion, radical excision is difficult. Because there is no statistically significant difference in recurrence rate between radical and restricted excision, radical resection may not be the best option ( 3 , 7 – 11 ).…”

Section: Discussionmentioning

confidence: 99%

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Aggressive angiomyxoma of the pelvis and abdominal wall: Dramatic response to chemical ablation therapy

Liu

et al. 2023

Front. Oncol.

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ObjectiveAggressive angiomyxoma (AAM) is a rare, locally aggressive soft tissue neoplasm with a marked tendency for local recurrence after surgery. Although hormone therapy, radiation therapy, and vascular embolization can be performed, we investigated the safety and efficacy of a new chemical ablation protocol for AAM.MethodsThis study included two female AAM patients from 2012 to 2016. The patients’ clinical and imaging data were collected. The amount of anhydrous ethanol and glacial acetic acid used for chemical ablation was documented, and the management of any complications was detailed.ResultsThe maximum dimensions of the residual tumor were 12.6 cm and 14.0 cm. In one case, the lesion was in the pelvis and protruded into the vulva. Eighty milliliters of liquid with a mixture of glacial acetic acid, anhydrous ethanol, and iohexol (10:9:1) was used for chemical ablation therapy via multipoint injections with a single needle. However, a pelvic fistula developed 1 month later. In another case, the lesion was located in the abdominal wall. The ablation procedure was improved by performing chemical ablation therapy with multiple needles for multi-point injections of smaller than 30 ml injections for each procedure. To date, no recurrence or metastasis has been observed in the two cases.ConclusionThe preferred treatment for AAM is complete resection. Chemical ablation therapy is a novel adjuvant therapy for AMM. Nonetheless, more research is needed to confirm these findings.

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Section: Discussionmentioning

confidence: 99%

“…Radiotherapy, GnRH therapy, and other approaches have already been reported to address residual tumors (3)(4)(5), but the local control rates are poor. We report two cases of residual AAM that were treated with chemical ablation therapy.…”

Section: Introductionmentioning

confidence: 99%