In this investigative study, the Taguchi design (L9) of experiments with TOPSIS multi-objective optimization is used for the robot nanopainting. The optimization objective is to maximize the film glue individually and minimize the surface blemishes and film thickness by varying the IRB 1410 robot painting parameters, such as the robot speed, pressure, and distance. The multi-wall carbon nanotube is infused into the paint materials using the ultrasonication process, and the mechanical properties are analysed with a comparison to regular paint materials. The virtual robot cycle time analysis is carried out for three different robot pathway patterns, namely linear, zig-zag, and circular. It is then compared with real-time experimental robot nanopaint on cold rolled close annealing steel materials. The obtained results show that surface roughness and thickness are minimized by 54% and 33.4%, respectively, using the robot nano spray coating when compared with regular spray coating. The film adhesive of robot Nano spray coating is maximized by 2.8% more than normal spray coating. A fuzzy logic expert system model is used to evaluate the surface finish characteristics of the nanopaint surface with low prediction error and with 89.2% confidence level. Heat transfer analysis of the robot nano-coated substrate is compared with that of the robot normal-coated substrate.